ArticleScientific reports2023
Reproducibility of the computational fluid dynamic analysis of a cerebral aneurysm monitored over a decade.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Artificial Intelligence for Cerebral Aneurysm Management: Integrating Imaging, Hemodynamics, and Clinical Decision Support.Journal of imaging informatics in medicine · 2026Review
- From hemodynamic stress to inflammatory wall remodeling in intracranial aneurysms.Frontiers in molecular biosciences · 2026Review
- Integrating Laplace's law with patient-specific hemodynamics to predict rupture risk in unruptured intracranial aneurysms: A systematic review of a biophysical and computational framework.Surgery in practice and science · 2025Review
- Haemodynamic characteristics of thin-walled regions in intracranial aneurysms: intraoperative imaging and CFD analysis.Acta neurochirurgica · 2025Article
- A Review of Intracranial Aneurysm Imaging Modalities, from CT to State-of-the-Art MR.AJNR. American journal of neuroradiology · 2025Review
- Correlation of plasma plectin levels with small intracranial aneurysms instability and prognosis.Neurosurgical review · 2025Article
- Comparison of ELAPSS Score and Computational Fluid Dynamics for Predicting Growth of Small Unruptured Cerebral Aneurysms.Neurologia medico-chirurgica · 2025Observational
- Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Estimating flow division in aortic branches of diseased aorta: a method for boundary condition specification in CFD analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Intra-abdominal temperature variation during hyperthermic intraperitoneal chemotherapy evaluated via computational fluid dynamics modeling.Journal of gastrointestinal oncology · 2024Article
- Time-of-Flight MRA of Intracranial Aneurysms with Interval Surveillance, Clinical Segmentation and Annotations.Scientific data · 2024Article
- Analysis of Intracranial Aneurysm Haemodynamics Altered by Wall Movement.Bioengineering (Basel, Switzerland) · 2024Article
- Decoding the Cell Atlas and Inflammatory Features of Human Intracranial Aneurysm Wall by Single-Cell RNA Sequencing.Journal of the American Heart Association · 2024Article
- Article
- MeshGrow: Integrated framework for simulation-ready cardiac and vascular mesh construction from medical imaging.JRSM cardiovascular diseaseArticle
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Computational fluid dynamics (CFD) simulations are increasingly utilised to evaluate intracranial aneurysm (IA) haemodynamics to aid in the prediction of morphological changes and rupture risk. However, these models vary and differences in published results warrant the investigation of IA-CFD reproducibility. This study aims to explore sources of intra-team variability and determine its impact on the aneurysm morphology and CFD parameters. A team of four operators were given six sets of magnetic resonance angiography data spanning a decade from one patient with a middle cerebral aneurysm. All operators were given the same protocol and software for model reconstruction and numerical analysis. The morphology and haemodynamics of the operator models were then compared. The segmentation, smoothing factor, inlet and outflow branch lengths were found to cause intra-team variability. There was 80% reproducibility in the time-averaged wall shear stress distribution among operators with the major difference attributed to the level of smoothing. Based on these findings, it was concluded that the clinical applicability of CFD simulations may be feasible if a standardised segmentation protocol is developed. Moreover, when analysing the aneurysm shape change over a decade, it was noted that the co-existence of positive and negative values of the wall shear stress divergence (WSSD) contributed to the growth of a daughter sac.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.