Evidence map›Paper›PMID 36604450›Full record

ArticleScientific reports2023

Bald eagle mortality and nest failure due to clade 2.3.4.4 highly pathogenic H5N1 influenza a virus.

Nicole M Nemeth, Mark G Ruder, Rebecca L Poulson, Robert Sargent, Shawnlei Breeding, Meaghan N Evans, Jared Zimmerman, Rebecca Hardman, Mark Cunningham, Samantha Gibbs and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 67 citations in OpenAlex.

  1. Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  2. Contrast-Enhanced CT of the Coelom in a Female Bald Eagle (Animals : an open access journal from MDPI · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Nicole M NemethSoutheastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA. nmnemeth@uga.edu.
Mark G RuderSoutheastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.
Rebecca L PoulsonSoutheastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.
Robert SargentGeorgia Department of Natural Resources, Wildlife Resources Division, Georgia, Forsyth, GA, 31029, USA.
Shawnlei BreedingAudubon Center for Birds of Prey, 1101 Audubon Way, Maitland, FL, 32751, USA.
Meaghan N EvansFish and Wildlife Research Institute, Florida Fish and Wildlife Conservation Commission, Gainesville, FL, 32601, USA.
Jared ZimmermanFish and Wildlife Research Institute, Florida Fish and Wildlife Conservation Commission, Gainesville, FL, 32601, USA.
Rebecca HardmanFish and Wildlife Research Institute, Florida Fish and Wildlife Conservation Commission, Gainesville, FL, 32601, USA.
Mark CunninghamFish and Wildlife Research Institute, Florida Fish and Wildlife Conservation Commission, Gainesville, FL, 32601, USA.
Samantha GibbsWildlife Health Office, National Wildlife Refuge System, United States Fish and Wildlife Service, Chiefland, FL, 32626, USA.
David E StallknechtSoutheastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.
Florida Fish and Wildlife Conservation Commission · USUniversity of Georgia · USAudubon Nature Institute · USGeorgia Department of Natural Resources · USUnited States Fish and Wildlife Service · US

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4M
NIAID NIH HHS 75N93021C00016NIH HHS 75N93021C00016
6 · The paper itself

Abstract

The bald eagle (Haliaeetus leucocephalus) is a culturally and ecologically vital species in North America that embodies conservation success but continues to face threats that include emerging pathogens. The introduction of A/goose/Guangdong/1/1996 lineage highly pathogenic (HP) clade 2.3.4.4b H5N1 influenza A virus (IAV) in North America in late 2021 resulted in high rates of mortality among bald eagles. Here we show an alarming rate of bald eagle nest failure and mortality attributed to HP IAV. We documented fatal, systemic HP IAV infection in breeding adult and nestling bald eagles along the southeastern U.S. coast. Concurrently, annual bald eagle nest surveys in Georgia and Florida revealed a precipitous drop in success in coastal counties compared with previous years, portending negative impacts on population recruitment. As an apex predator and efficient scavenger, it is likely that bald eagles become infected through consumption of infected waterfowl. These results and similar reports of raptor mortality in Europe, Asia, and Africa, indicate a clear threat to raptor health. The possible long-term persistence of HP H5N1 IAV in North America poses an impending threat to bald eagle populations not only related to direct mortality but also decreased recruitment and warrants continued efforts to understand these potential impacts.

Indexed as

EaglesInfluenza A Virus, H5N1 SubtypeAnimalsFloridaGeorgiaNorth America

Identifiers

PMID36604450
PMCPMC9813463
OpenAlexW4313571881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.