Evidence map›Paper›PMID 36604444›Full record

ArticleNature communications2023

Natural oxidase-mimicking copper-organic frameworks for targeted identification of ascorbate in sensitive sweat sensing.

Zhengyun Wang, Yuchen Huang, Kunqi Xu, Yanyu Zhong, Chaohui He, Lipei Jiang, Jiankang Sun, Zhuang Rao, Jiannan Zhu, Jing Huang and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Recent Advances in Reactive Microdroplets for Clean Water and Energy.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  7. Biomedical Applications of Nanozymes: An Enzymology Perspective.Angewandte Chemie (International ed. in English) · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Electrochemical Detection ofSensors (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhengyun WangHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Yuchen HuangSecretariat license de chimie, bâtiment 460, Université Paris-saclay, 91400, Orsay, Paris, France.
Kunqi XuKey Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 201899, Shanghai, PR China.
Yanyu ZhongHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Chaohui HeHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Lipei JiangHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Jiankang SunHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Zhuang RaoHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Jiannan ZhuHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Jing HuangHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Fei XiaoHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China.
Hongfang LiuHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China. liuhf@hust.edu.cn.ORCID 0000-0001-5012-7278
Bao Yu XiaHubei Key Laboratory of Material Chemistry and Service Failure, Key Laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd, 430074, Wuhan, PR China. byxia@hust.edu.cn.ORCID 0000-0002-2054-908X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sweat sensors play a significant role in personalized healthcare by dynamically monitoring biochemical markers to detect individual physiological status. The specific response to the target biomolecules usually depends on natural oxidase, but it is susceptible to external interference. In this work, we report tryptophan- and histidine-treated copper metal-organic frameworks (Cu-MOFs). This amino-functionalized copper-organic framework shows highly selective activity for ascorbate oxidation and can serve as an efficient ascorbate oxidase-mimicking material in sensitive sweat sensors. Experiments and calculation results elucidate that the introduced tryptophan/histidine fundamentally regulates the adsorption behaviors of biomolecules, enabling ascorbate to be selectively captured from complex sweat and further efficiently electrooxidized. This work provides not only a paradigm for specifically sweat sensing but also a significant understanding of natural oxidase-inspired MOF nanoenzymes for sensing technologies and beyond.

Indexed as

OxidoreductasesSweatCopperHistidineTryptophanCopperHistidineOxidoreductasesTryptophan

Identifiers

PMID36604444
PMCPMC9814535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.