Evidence map›Paper›PMID 36604322›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023

Autologous semitendinosus meniscus graft significantly improves knee joint kinematics and the tibiofemoral contact after complete lateral meniscectomy.

Andreas M Seitz, Janina Leiprecht, Jonas Schwer, Anita Ignatius, Heiko Reichel, Thomas Kappe

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07204587 (A Stratified, Partially Randomized Study Comparing Autologous Semitendinosus Tendon Graft and Meniscal Allograft Transplantation in Young Adults With Post-Meniscectomy Syndrome), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07204587 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Stratified, Partially Randomized Study Comparing Autologous Semitendinosus Tendon Graft and Meniscal Allograft Transplantation in Young Adults With Post-Meniscectomy Syndrome

TypeinterventionalSponsorChang Gung Memorial HospitalRan2025 to 2029Enrolled40ConditionsMeniscal Injuries, Meniscal Tear, Meniscus LesionArmsAutologous Semitendinosus Tendon Graft, Meniscal Allograft Transplantation (MAT)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andreas M SeitzInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, University Medical Center, Ulm University, Helmholtzstrasse 14, 89081, Ulm, Germany. andreas.seitz@uni-ulm.de.ORCID http://orcid.org/0000-0001-8174-8552
Janina LeiprechtDepartment of Orthopedic Surgery, RKU, Ulm University Medical Center, Ulm, Germany.
Jonas SchwerInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, University Medical Center, Ulm University, Helmholtzstrasse 14, 89081, Ulm, Germany.
Anita IgnatiusInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, University Medical Center, Ulm University, Helmholtzstrasse 14, 89081, Ulm, Germany.
Heiko ReichelDepartment of Orthopedic Surgery, RKU, Ulm University Medical Center, Ulm, Germany.
Thomas KappeDepartment of Orthopedic Surgery, RKU, Ulm University Medical Center, Ulm, Germany.
Helmholtz-Institute Ulm · DEUniversität Ulm · DE

Funding

Deutschen Arthrose-Hilfe P507
6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the potential of a doubled semitendinosus (ST) and a single gracilis tendon (GT) lateral meniscus autograft to restore the knee joint kinematics and tibiofemoral contact after total lateral meniscectomy (LMM).

methodsFourteen human knee joints were tested intact, after LMM and after ST and GT meniscus autograft treatment under an axial load of 200 N during full range of motion (0°-120°) and four randomised loading situations: without external moments, external rotation, valgus stress and a combination of external rotation and valgus stress using a knee joint simulator. Non-parametric statistical analyses were performed on joint kinematics and on the tibiofemoral contact mechanics.

resultsLMM led to significant rotational instability of the knee joints (p < 0.02), which was significantly improved after ST autograft application (p < 0.04), except for knee joint flexions > 60°. The GT autograft failed to restore the joint kinematics. LMM significantly increased the tibiofemoral contact pressure (p < 0.03), while decreasing the contact area (p < 0.05). The ST autograft was able to restore the contact mechanics after LMM (p < 0.02), while the GT replacement displayed only an improvement trend.

conclusionThe doubled ST lateral meniscus autograft improved the knee joint kinematics significantly and restored the tibiofemoral contact mechanics almost comparable to the native situation. Thus, from a biomechanical point of view, ST meniscus autografts might be a potential treatment alternative for patients who are indicated for meniscus allograft transplantation.

Indexed as

Hamstring MusclesTibial Meniscus InjuriesBiomechanical PhenomenaCadaverHumansKnee JointMeniscectomyMenisci, TibialRange of Motion, ArticularTibiaKinematicsLateral meniscusMeniscectomyTendon autograftTibiofemoral contactTotal replacement

Identifiers

PMID36604322
PMCPMC10276070
OpenAlexW4313553279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.