Evidence map›Paper›PMID 36604142›Full record

ArticleActa biochimica et biophysica Sinica2022

MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors.

Zeng Ye, Haidi Chen, Shunrong Ji, Yuheng Hu, Xin Lou, Wuhu Zhang, Desheng Jing, Guixiong Fan, Yue Zhang, Xuemin Chen and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Metabolic changes in neuroendocrine neoplasms.Cellular and molecular life sciences : CMLS · 2025
    Review
  9. Review
  10. Article
  11. Menin in Cancer.Genes · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Zeng YeCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Haidi ChenCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Shunrong JiCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yuheng HuCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xin LouCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Wuhu ZhangCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Desheng JingCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Guixiong FanCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yue ZhangDepartment of Hepatobiliary and Pancreatic Surgery, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.
Xuemin ChenDepartment of Hepatobiliary and Pancreatic Surgery, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.
Qifeng ZhuoCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Jie ChenCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xiaowu XuCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xianjun YuCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Jin XuCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yi QinCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Heli GaoCenter for Neuroendocrine Tumors, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Fudan University Shanghai Cancer Center · CNShanghai Cancer Institute · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine tumor (pNET) is the second most common malignant tumors of the pancreas. Multiple endocrine neoplasia 1 (

Indexed as

FerroptosisNeuroendocrine TumorsPancreatic NeoplasmsProto-Oncogene ProteinsEverolimusHumansStearoyl-CoA DesaturaseTOR Serine-Threonine KinasesTranscription FactorsEverolimusMEN1 protein, humanMTOR protein, humanProto-Oncogene ProteinsSCD1 protein, humanStearoyl-CoA DesaturaseTOR Serine-Threonine KinasesTranscription FactorsferroptosisMEN1mTOR signalingpancreatic neuroendocrine tumorSCD1

Identifiers

PMID36604142
PMCPMC9828289
OpenAlexW4308589300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.