Evidence map›Paper›PMID 36604137›Full record

SynthesisBMJ open2023

Effect of polyphenol compounds on

Qiuxiang Wang, Chengjiao Yao, Yilin Li, Lihong Luo, Fengjiao Xie, Qin Xiong, Peimin Feng

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. BiombalanceAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. The effects and mechanisms of natural products onFrontiers in cellular and infection microbiology · 2024
    Review
  7. A review for non-antibiotic treatment ofFrontiers in microbiology · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Qiuxiang WangChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID 0000-0002-6316-8279
Chengjiao YaoDepartment of Geriatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.ORCID 0000-0002-7716-368X
Yilin LiChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Lihong LuoChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID 0000-0001-9055-1137
Fengjiao XieChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID 0000-0003-4344-0973
Qin XiongChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID 0000-0003-2846-7369
Peimin FengAffiliated hospital of Chengdu university of traditional Chinese medicine, Chengdu, Sichuan, China fpmvv@126.com.
Chengdu University of Traditional Chinese Medicine · CNAffiliated Hospital of North Sichuan Medical College · CNSecond Affiliated Hospital of Chengdu University of Traditional Chinese · CNTaiyuan Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPolyphenol compounds are classified as organic compounds with phenolic units exhibiting a variety of biological functions. This meta-analysis aims to assess the efficacy and safety of polyphenol compounds (curcumin, cranberry, garlic, liquorice and broccoli) in eradicating

designSystematic review and meta-analysis.

methodsLiterature searches were conducted on PubMed, Embase, The Cochrane Library, Web of Science, Medline, Chinese National Knowledge Infrastructure database, Chinese Scientific Journal Database and Wan Fang database from inception to January 2022. All randomised controlled trials comparing polyphenol compounds with the placebo or used as an adjunct treatment are included in this meta-analysis.The treatment effect for dichotomous outcomes was assessed using risk ratio (RR), while for continuous outcomes, mean differences both with 95% CIs, were used. Subgroup analyses were carried out for different treatment schemes and polyphenol compound species.

results12 trials were included in the meta-analysis. The total eradication rate of

conclusionPolyphenol compounds can improve PROSPERO REGISTRATION NUMBER: CRD42022307477.

Indexed as

Helicobacter InfectionsHelicobacter pyloriAmoxicillinAnti-Bacterial AgentsDrug Therapy, CombinationHumansPolyphenolsAmoxicillinAnti-Bacterial AgentsPolyphenolsAdult gastroenterologyGASTROENTEROLOGYGastrointestinal infections

Identifiers

PMID36604137
PMCPMC9827256
OpenAlexW4313560749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.