ArticleMayo Clinic proceedings2023
Association of Combined Healthy Lifestyles With Cardiovascular Disease and Mortality of Patients With Diabetes: An International Multicohort Study.
Article in Mayo Clinic proceedings, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Dietary Patterns and Cardiovascular Diseases in Individuals with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Prospective Observational Studies.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- Exploring medication self-management in polypharmacy: a qualitative systematic review of patients and healthcare providers perspectives.Frontiers in pharmacology · 2024Pooled it
- Lifestyle profiles and long-term blood pressure control are associated with lower risks of stroke and all-cause mortality among treated hypertensive patients: findings from the China Stroke Primary Prevention Trial.Journal of human hypertension · 2026Trial
- Mediterranean lifestyle and risk of adverse cardiovascular events, all-cause and cardiovascular mortality among individuals with type 2 diabetes.EClinicalMedicine · 2026Article
- The combined impact of social isolation and unhealthy risk score on mortality risk: a study from two prospective cohorts.BMC public health · 2026Article
- Association of healthy lifestyle with tooth count among adults aged 20 years and above: a cross-sectional study.BMC oral health · 2026Article
- Joint associations of multiple healthy lifestyles with the risk of cardiovascular disease: a prospective cohort study of UK Biobank.European journal of public health · 2026Article
- The association of incident abdominal obesity with diet and unfavorable lifestyle factors in Korean adults: A prospective cohort study.Medicine · 2026Observational
- Problematic smartphone use in college students: the interplay of adverse childhood experiences and lifestyle factors.Frontiers in public health · 2026Article
- Histidine-Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Article
- Anti-inflammatory diets might mitigate the association between sedentary behaviors and the risk of all-cause deaths.Nutrition & metabolism · 2025Article
- Association of oxidative balance score with the risk of all-cause and CVD mortality in younger US adults with diabetes.Scientific reports · 2025Article
- Association between combined healthy lifestyles and infertility: a cross-sectional study in US reproductive-aged women.BMC public health · 2025Article
- Health behavior and disease self-management indicators in patients with cardiovascular diseases using a health app: Findings from an RCT.AIMS public health · 2025Article
- Comparative Effects of Exercise and GLP-1 RAs on Type 2 Diabetic Rat Model: A Systematic Review.International journal of exercise science · 2025Review
- Prediction of Major Adverse Coronary Events Using the Coronary Risk Score in Women.Radiology. Cardiothoracic imaging · 2024Article
- Association of healthy lifestyles with risk of all-cause and cause-specific mortality among individuals with metabolic dysfunction-associated steatotic liver disease: results from the DFTJ cohort.Annals of medicine · 2024Article
- Healthy lifestyle associated with dynamic progression of type 2 diabetes: A multi-state analysis of a prospective cohort.Journal of global health · 2024Article
- The Effect of Statins on Carotid Intima-Media Thickness and C-Reactive Protein in Type 2 Diabetes Mellitus: A Meta-Analysis.Journal of cardiovascular development and disease · 2024Review
- Physical Activity Modifies the Risk of Incident Cardiac Conduction Disorders Upon Inflammation: A Population-Based Cohort Study.Journal of the American Heart Association · 2024Article
Corrections and comments
- Commented on by
Authors and funding
27 authors.
Funding
Abstract
objectiveTo prospectively examine the associations of combined lifestyle factors with incident cardiovascular disease (CVD) and mortality in patients with diabetes. PATIENTS AND
methodsPatients with prevalent diabetes were included from 5 prospective, population-based cohorts in China (Dongfeng-Tongji cohort and Kailuan study), the United Kingdom (UK Biobank study), and the United States (National Health and Nutrition Examination Survey and National Institutes of Health-AARP Diet and Health Study). Healthy lifestyle scores were constructed according to non-current smoking, low to moderate alcohol drinking, regular physical activity, healthy diet, and optimal body weight; the healthy level of each lifestyle factor was assigned 1 point, or 0 for otherwise, and the range of the score was 0 to 5. Cox proportional hazards models were used to estimate hazard ratios for incident CVD, CVD mortality, and all-cause mortality adjusting for sociodemographic, medical, and diabetes-related factors, and outcomes were obtained by linkage to medical records and death registries. Data were collected from October 18, 1988, to September 30, 2020.
resultsA total of 6945 incident CVD cases were documented in 41,350 participants without CVD at baseline from the 2 Chinese cohorts and the UK Biobank during 389,330 person-years of follow-up, and 40,353 deaths were documented in 101,219 participants from all 5 cohorts during 1,238,391 person-years of follow-up. Adjusted hazard ratios (95% CIs) comparing patients with 4 or 5 vs 0 or 1 healthy lifestyle factors were 0.67 (0.60 to 0.74) for incident CVD, 0.58 (0.50 to 0.68) for CVD mortality, and 0.60 (0.53 to 0.68) for all-cause mortality. Findings remained consistent across different cohorts, subgroups, and sensitivity analyses.
conclusionThe international analyses document that adherence to multicomponent healthy lifestyles is associated with lower risk of CVD and premature death of patients with diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.