Evidence map›Paper›PMID 36603956›Full record

ArticleMayo Clinic proceedings2023

Characteristics, Treatment Patterns, and Clinical Outcomes After Heart Failure Hospitalizations During the COVID-19 Pandemic, March to October 2020.

Mohammed Yousufuddin, Mohamad H Yamani, Kianoush B Kashani, Ye Zhu, Zhen Wang, Ashok Seshadri, Katherine R Blocker, Jessica L Peters, Jewell M Doss, Dhauna Karam and 17 more

Abstract readMulticenter Study
In one paragraph

Article in Mayo Clinic proceedings, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Comorbidity patterns and mortality in HFpEF: A retrospective longitudinal cohort study.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Mohammed YousufuddinDivision of Hospital Internal Medicine, Mayo Clinic Health System, Austin, MN. Electronic address: Yousufuddin.mohammed@Mayo.edu.
Mohamad H YamaniDivision of Cardiology, Mayo Clinic, Jacksonville, FL.
Kianoush B KashaniDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.
Ye ZhuRobert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
Zhen WangRobert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
Ashok SeshadriDivision of Psychiatry, Mayo Clinic Health System, Austin, MN.
Katherine R BlockerDivision of Hospital Internal Medicine, Mayo Clinic Health System, Austin, MN.
Jessica L PetersDivision of Hospital Internal Medicine, Mayo Clinic Health System, Austin, MN.
Jewell M DossDivision of Hospital Internal Medicine, Mayo Clinic Health System, Austin, MN.
Dhauna KaramDivision of Hospital Internal Medicine, Mayo Clinic Health System, Austin, MN.
Kanika KhandelwalDivision of Hospital Internal Medicine, Mayo Clinic Health System, Austin, MN.
Umesh M SharmaHospital Internal Medicine, Mayo Clinic, Phoenix, AZ.
Daniel V DudenkovDivision of General Internal Medicine, Mayo Clinic, Jacksonville, FL.
Tahir MehmoodDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN.
Sandeep R PagaliDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN.
Sanjeev NandaDivision of General Internal Medicine, Mayo Clinic, Rochester, MN.
Ahmed D AbdalrhimDivision of General Internal Medicine, Mayo Clinic, Rochester, MN.
Nichole CummingsDivision of Hospital Internal Medicine, St. Cloud Hospital, St. Cloud, MN.
Sagar B DuganiDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN.
Michael SmerinaDivision of General Internal Medicine, Mayo Clinic, Jacksonville, FL.
Larry J ProkopLibrary and Public Services, Mayo Clinic, Rochester, MN.
Lawrence R KeenanDivision of Cardiology, Mayo Clinic Health System, Austin, MN.
Sumit BhagraDivision of Endocrinology, Mayo Clinic Health System, Austin, MN.
Arshad JahangirAurora Cardiovascular and Thoracic Services, Aurora St. Luke's Medical Center, Milwaukee, WI.
Philippe R BauerDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Gregg C FonarowDivision of Cardiology, University of California Los Angeles, Los Angeles, CA.
Mohammad Hassan MuradRobert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN; Division of Preventive and Occupational Medicine, Mayo Clinic, Rochester, MN.

Funding

Rural Patient Risks and Exposures for Diabetes ConTrol (Rural PREDICT)K23MD016230 · NIMHD · MAYO CLINIC ROCHESTER · PI DUGANI, CHANDRASAGAR · 2021 to 2025
$763k
NIMHD NIH HHS K23 MD016230
6 · The paper itself

Abstract

objectiveTo compare clinical characteristics, treatment patterns, and 30-day all-cause readmission and mortality between patients hospitalized for heart failure (HF) before and during the coronavirus disease 2019 (COVID-19) pandemic. PATIENTS AND

methodsThe study was conducted at 16 hospitals across 3 geographically dispersed US states. The study included 6769 adults (mean age, 74 years; 56% [5033 of 8989] men) with cumulative 8989 HF hospitalizations: 2341 hospitalizations during the COVID-19 pandemic (March 1 through October 30, 2020) and 6648 in the pre-COVID-19 (October 1, 2018, through February 28, 2020) comparator group. We used Poisson regression, Kaplan-Meier estimates, multivariable logistic, and Cox regression analysis to determine whether prespecified study outcomes varied by time frames.

resultsThe adjusted 30-day readmission rate decreased from 13.1% (872 of 6648) in the pre-COVID-19 period to 10.0% (234 of 2341) in the COVID-19 pandemic period (relative risk reduction, 23%; hazard ratio, 0.77; 95% CI, 0.66 to 0.89). Conversely, all-cause mortality increased from 9.7% (645 of 6648) in the pre-COVID-19 period to 11.3% (264 of 2341) in the COVID-19 pandemic period (relative risk increase, 16%; number of admissions needed for one additional death, 62.5; hazard ratio, 1.19; 95% CI, 1.02 to 1.39). Despite significant differences in rates of index hospitalization, readmission, and mortality across the study time frames, the disease severity, HF subtypes, and treatment patterns remained unchanged (P>0.05).

conclusionThe findings of this large tristate multicenter cohort study of HF hospitalizations suggest lower rates of index hospitalizations and 30-day readmissions but higher incidence of 30-day mortality with broadly similar use of HF medication, surgical interventions, and devices during the COVID-19 pandemic compared with the pre-COVID-19 time frame.

Indexed as

COVID-19Heart FailureAdultAgedCohort StudiesHospitalizationHumansMalePandemicsPatient Readmission

Identifiers

PMID36603956
PMCPMC9489984

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.