Evidence map›Paper›PMID 36603847›Full record

ArticleJournal of the American Society for Mass Spectrometry2023

Novel Hybrid Quadrupole-Multireflecting Time-of-Flight Mass Spectrometry System.

Dale A Cooper-Shepherd, Jason Wildgoose, Boris Kozlov, William J Johnson, Richard Tyldesley-Worster, Martin E Palmer, John B Hoyes, Michael McCullagh, Emrys Jones, Robert Tonge and 4 more

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Stable Isotope Tracing Primer for the Mass Spectrometrist.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026
    Review
  5. A Novel Compact Multi-Reflecting Time-of-Flight Mass Spectrometer.Journal of the American Society for Mass Spectrometry · 2026
    Article
  6. Mass Spectrometry Imaging.Analytical chemistry · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Spatial pharmacology using mass spectrometry imaging.Trends in pharmacological sciences · 2024
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dale A Cooper-ShepherdWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.ORCID 0000-0001-9301-1777
Jason WildgooseWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Boris KozlovWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
William J JohnsonWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Richard Tyldesley-WorsterWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Martin E PalmerWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.ORCID 0000-0003-1658-9334
John B HoyesWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Michael McCullaghWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.ORCID 0000-0003-4785-1745
Emrys JonesWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.ORCID 0000-0001-9834-217X
Robert TongeWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Emma Marsden-EdwardsWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Peter NixonWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.
Anatoly VerenchikovMSC-CG Ltd, Novi Bulevar A5, Bar85000, Montenegro.
James I LangridgeWaters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire, U.K.SK9 4AX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel mass spectrometry system is described here comprising a quadrupole-multireflecting time-of-flight design. The new multireflecting time-of-flight analyzer has an effective path length of 48 m and employs planar, gridless ion mirrors providing fourth-order energy focusing resulting in resolving power over 200 000 fwhm and sub-ppm mass accuracy. We show how these attributes are maintained with relatively fast acquisition speeds, setting the system apart from other high resolution mass spectrometers. We have integrated this new system into both liquid chromatography-mass spectrometry and mass spectrometry imaging workflows to demonstrate how the instrument characteristics are of benefit to these applications.

Identifiers

PMID36603847
PMCPMC9896552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.