Evidence map›Paper›PMID 36603363›Full record

ReviewDrug and alcohol dependence2023

A review of factors associated with methadone maintenance treatment adherence and retention in Vietnam.

Thuong Nong, Dominic Hodgkin, Nguyen Thu Trang, Steven J Shoptaw, Michael J Li, Hoang Thi Hai Van, Giang Le

Abstract readReview
In one paragraph

Review in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Perspectives on addiction-related problems in Vietnam.Addiction (Abingdon, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thuong NongThe Heller School for Social Policy and Management, Brandeis University, 415 South St, Waltham, MA 02453, the United States of America. Electronic address: thuongnong@brandeis.edu.
Dominic HodgkinThe Heller School for Social Policy and Management, Brandeis University, 415 South St, Waltham, MA 02453, the United States of America.
Nguyen Thu TrangCenter for Training and Research on Substance Abuse and HIV, Hanoi Medical University, Hanoi, Viet Nam.
Steven J ShoptawCenter for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, the United States of America.
Michael J LiCenter for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, the United States of America.
Hoang Thi Hai VanGlobal Health Department, Hanoi Medical University, Hanoi, Viet Nam.
Giang LeCenter for Training and Research on Substance Abuse and HIV, Hanoi Medical University, Hanoi, Viet Nam.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Screen, Treat and Retain People with Primary Meth Use Disorder at MMT Clinics (STAR-OM+)R01DA050486 · NIDA · HANOI MEDICAL UNIVERSITY · PI LE, GIANG M, SHOPTAW, STEVEN J · 2020 to 2024
$2.3M
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency managementK01DA051329 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, MICHAEL JONATHAN · 2021 to 2025
$947k
NIDA NIH HHS K01 DA051329NIDA NIH HHS R01 DA050486NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundStarting in 2008, Vietnam's national MMT program expanded quickly, but it is struggling with increasing attrition rates and poor adherence among patients. Several studies have reported on MMT retention and adherence, but no overview has yet been published. The objective of this study is to fill that gap and to review factors associated with retention and adherence in MMT in Vietnam.

methodsA systematic search was conducted using databases of literature - Pubmed, Cochrane, Scopus, Academic search premiere, and SoINDEX. Peer-reviewed empirical studies with full text in English discussing retention attrition and adherence regarding MMT in Vietnam were selected. The results were synthesized using qualitative methods.

resultsAdherence and retention rates varied among the 11 included studies. In general, patients in mountainous provinces had lower adherence and retention rates than those in big cities. Retention rates decreased with the studies' follow-up period and had a downward trend over time. Factors associated with adherence and retention can be classified into three groups: individual, community, and institutional factors. Important individual factors areage, education, awareness of MMT and HIV, and co-occurring disorders and comorbidities. Stigma is the major community risk factor, and methadone daily dose, the distance between home and clinic, and clinic's service hours are the three most important institutional factors.

conclusionsThe literature reviewed identifies important factors associated with MMT adherence and retention in Vietnam. The findings suggest further research exploring both subjective and objective factors and more policies to remove social and structural barriers to enhance treatment outcomes.

Indexed as

MethadoneOpiate Substitution TreatmentHumansRisk FactorsTreatment Adherence and ComplianceVietnamMethadoneAdherenceAttritionMethadone maintenance treatmentMMTRetention

Identifiers

PMID36603363
PMCPMC9851667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.