Evidence map›Paper›PMID 36603242›Full record

ArticleJournal of inorganic biochemistry2023

Incorporation of a molybdenum atom in a Rubredoxin-type Centre of a de novo-designed α

Pedro M S Bragança, Marta S P Carepo, Sofia R Pauleta, Tyler B J Pinter, Maddalena Elia, Cristina M Cordas, Isabel Moura, Vincent L Pecoraro, José J G Moura

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pedro M S BragançaLAQV, REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; Microbial Stress Lab, UCIBIO - Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Marta S P CarepoLAQV, REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; Escola de Psicologia e Ciências da Vida, Departamento de Ciências da Vida, Universidade Lusófona de Humanidades e Tecnologias, Campo Grande, 1749-024 Lisboa, Portugal. Electronic address: marta.carepo@fct.unl.pt.
Sofia R PauletaMicrobial Stress Lab, UCIBIO - Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Tyler B J PinterDepartment of Chemistry and Biophysics, University of Michigan, Ann Arbor, MI 48109-1055, United States.
Maddalena EliaLAQV, REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Cristina M CordasLAQV, REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Isabel MouraLAQV, REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Vincent L PecoraroDepartment of Chemistry and Biophysics, University of Michigan, Ann Arbor, MI 48109-1055, United States.
José J G MouraLAQV, REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal. Electronic address: jose.moura@fct.unl.pt.

Funding

Designing Functional Metalloproteins-Equipment SupplementR01GM141086 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PECORARO, VINCENT L · 2021 to 2024
$1.3M
NIGMS NIH HHS R01 GM141086
6 · The paper itself

Abstract

The rational design and functionalization of small, simple, and stable peptides scaffolds is an attractive avenue to mimic catalytic metal-centres of complex proteins, relevant for the design of metalloenzymes with environmental, biotechnological and health impacts. The de novo designed α

Indexed as

MetalloproteinsMolybdenumOxidation-ReductionPeptidesRubredoxinsMetalloproteinsMolybdenumPeptidesRubredoxinsA de novo protein designModels of molybdenum-containing enzymesMolybdenumRubredoxinTetracysteinyl coordinationThree-helix bundle

Identifiers

PMID36603242
PMCPMC11232944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.