Evidence map›Paper›PMID 36603172›Full record

ArticleJCO precision oncology2023

Niamh Coleman, Kathrina L Marcelo, Julia F Hopkins, Nusrat Israr Khan, Robyn Du, Lingzhi Hong, Edward Park, Binaifer Balsara, Mollie Leoni, Curtis Pickering and 6 more

Open access · hybridAbstract read
In one paragraph

Article in JCO precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Renaissance of farnesyltransferase inhibitors in cancer.Journal of translational medicine · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. International journal of molecular sciences · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Niamh ColemanDepartment of Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-5803-9528
Kathrina L MarceloDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Julia F HopkinsCancer Genomics Research, Foundation Medicine Inc, Cambridge, MA.
Nusrat Israr KhanDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-6676-7269
Robyn DuDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0001-5075-9312
Lingzhi HongDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0001-6553-3279
Edward ParkClinical Development, Kura Oncology Inc, Boston, MA.ORCID 0000-0002-5078-0039
Binaifer BalsaraClinical Development, Kura Oncology Inc, Boston, MA.
Mollie LeoniClinical Development, Kura Oncology Inc, Boston, MA.
Curtis PickeringDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-7942-728X
Jeffrey MyersDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0003-4767-3408
John HeymachDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0001-9068-8942
Lee A AlbackerCancer Genomics Research, Foundation Medicine Inc, Cambridge, MA.ORCID 0000-0002-5070-1783
David HongDepartment of Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0001-8721-1609
Maura GillisonDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Xiuning LeDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-8554-1185
The University of Texas MD Anderson Cancer Center · USKura Oncology (United States) · USFoundation Medicine (United States)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn head and neck squamous cell carcinoma (HNSCC),

methodsWe leveraged four deidentified patient data sets with

resultsTwo hundred forty-nine patients with

conclusionOncogenic mutations in

Indexed as

Head and Neck NeoplasmsSquamous Cell Carcinoma of Head and NeckAgedHumansMaleMiddle AgedMutationNeoplasm Recurrence, LocalProto-Oncogene Proteins p21(ras)HRAS protein, humanProto-Oncogene Proteins p21(ras)

Identifiers

PMID36603172
PMCPMC9928766
OpenAlexW4313552742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.