Evidence map›Paper›PMID 36603001›Full record

ArticleAmerican journal of physiology. Renal physiology2023

The transcription factor Foxi1 promotes expression of V-ATPase and Gpr116 in M-1 cells.

Mackenzie Kui, Jennifer L Pluznick, Nathan A Zaidman

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Novel Roles of GPCRs in the Renal Collecting Duct.Physiology (Bethesda, Md.) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The K-Cl cotransporter-3 in the mammalian kidney.Current opinion in nephrology and hypertension · 2023
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mackenzie KuiDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Jennifer L PluznickDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0003-3621-2665
Nathan A ZaidmanDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0003-3864-6029
Johns Hopkins University · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
The Physiologic Role of Gpr116 in the KidneyF32DK116499 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZAIDMAN, NATHAN A · 2018 to 2020
$188k
Gpr116 Regulation of Renal Acid ExcretionK99DK127215 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZAIDMAN, NATHAN A · 2021 to 2022
$179k
Short Chain Fatty Acids (SCFAs) and SCFA G-protein Coupled Receptors in HypertensionR56DK107726 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI PLUZNICK, JENNIFER L · 2021 to 2021
$100k
NHLBI NIH HHS T32 HL007534NIDDK NIH HHS F32 DK116499NIDDK NIH HHS K99 DK127215NIDDK NIH HHS R56 DK107726
6 · The paper itself

Abstract

The diverse functions of each nephron segment rely on the coordinated action of specialized cell populations that are uniquely defined by their transcriptional profile. In the collecting duct, there are two critical and distinct cell populations: principal cells and intercalated cells. Principal cells play key roles in the regulation of water, Na

Indexed as

Forkhead Transcription FactorsReceptors, G-Protein-CoupledVacuolar Proton-Translocating ATPasesAdenosine TriphosphatasesAnimalsCell DifferentiationChloride-Bicarbonate AntiportersGene Expression RegulationKidneyMiceTranscription FactorsAdenosine TriphosphatasesAtp6v1b1 protein, mouseChloride-Bicarbonate AntiportersForkhead Transcription FactorsFoxi1 protein, mouseGpr116 protein, mouseReceptors, G-Protein-CoupledSlc4a9 protein, mouseTranscription FactorsVacuolar Proton-Translocating ATPasescollecting ductFoxi1G protein-coupled receptor 116intercalated cellsV-ATPase

Identifiers

PMID36603001
PMCPMC9942906
OpenAlexW4313546514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.