Evidence map›Paper›PMID 36602698›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2023

Bioconjugation of nanozyme and natural enzyme for ultrasensitive detection of cholesterol.

Hong-Tao Zhao, Jin-Ye Lang, Zhe Wang, Zhan-Song Hu, Chen-Chen Bai, Xian-Hua Wang

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hong-Tao ZhaoPharmaceutical Department of the Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Jin-Ye LangTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, Building B for School of Pharmacy, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin, 300072, China.
Zhe WangPharmaceutical Department of the Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Zhan-Song HuDepartment of Pharmacy of Tianjin Chest Hospital, Tianjin, 300350, China.
Chen-Chen BaiTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, Building B for School of Pharmacy, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin, 300072, China.
Xian-Hua WangTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, Building B for School of Pharmacy, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin, 300072, China. xianhua.w@163.com.ORCID http://orcid.org/0000-0002-1415-8285
Tianjin Medical University · CNSecond Hospital of Tianjin Medical University · CNTianjin Chest Hospital · CN

Funding

National Natural Science Foundation of China 21605114National Natural Science Foundation of China 82172829
6 · The paper itself

Abstract

When nanozymes are used in biological analysis, higher activity can improve the detection sensitivity, and better selectivity can eliminate other interference. To improve the specificity and sensitivity, we fabricated an innovative bioconjugated nanozyme with natural enzyme (BNNZ), in which natural ChOx was immobilized onto histidine-modified Fe

Indexed as

HistidineHydrogen PeroxideCholesterolColorimetryHumansPeroxidasePeroxidasesCholesterolHistidineHydrogen PeroxidePeroxidasePeroxidasesBioconjugationCascade reactionCholesterolNanozymeNatural enzyme

Identifiers

PMID36602698
OpenAlexW4313546515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.