Evidence map›Paper›PMID 36602652›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2023

Stem Cell Treatment Trials for Regeneration of Testicular Tissue in Laboratory Animals.

Hamdy Y Ismail, Shaymaa Hussein, Nora A Shaker, Hamdy Rizk, Y R Wally

Open access · hybridAbstract readReview
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Use of Stem Cells in Assisted Reproduction.Journal of clinical medicine · 2025
    Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hamdy Y IsmailDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Cairo University, 12211, Giza, Egypt. hamdy.yossef@cu.edu.eg.ORCID 0000-0001-5639-3390
Shaymaa HusseinDepartment of Cytology and Histology , Faculty of Veterinary Medicine, Cairo University, 12211, Giza, Egypt.
Nora A ShakerDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Cairo University, 12211, Giza, Egypt.
Hamdy RizkDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Cairo University, 12211, Giza, Egypt.
Y R WallyDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Cairo University, 12211, Giza, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility is a serious medical, economic, and psychological problem in the society. Male factor infertility, due to defective spermatogenesis as a result of a failure in germ cell proliferation and differentiation, appears to be the cause of 25-50% of infertility cases. According to several surveys, testicular degeneration can be caused by a variety of physical, chemical, and microbial causes. A stem cell is a non-specialized cell which is characterized by self-renewal by mitotic cell division and able to differentiate to specialized cells for the various tissues of the body. The data were obtained and analyzed from different databases (PubMed, Google Scholar, Egyptian Knowledge Bank, Elsevier, Medline, Embase, ProQuest, and BMC). This review discusses the causes, symptoms, and grades of testicular degeneration and the use of different types of stem cells in regeneration. And its conclusion based on previous researches and trials, MSCs are considered effective therapy for testicular degeneration.

Indexed as

Infertility, MaleTestisAnimalsAnimals, LaboratoryHumansMaleRegenerationSpermatogenesisStem CellsChemotherapyInfertilityLaboratory animalsStem cellTesticular degeneration

Identifiers

PMID36602652
PMCPMC10229736
OpenAlexW4313543609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.