ArticleApplied microbiology and biotechnology2023
Identification of a novel linear B-cell epitope in porcine deltacoronavirus nucleocapsid protein.
Article in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Development of a nucleocapsid protein-based competitive ELISA for the detection of porcine deltacoronavirus antibodies.Frontiers in microbiology · 2025Article
- Serial cell culture passagingJournal of virology · 2024Article
- Preparation and Epitope Identification of Monoclonal Antibodies against the NS6 Protein of Porcine Deltacoronavirus (PDCoV).International journal of molecular sciences · 2024Article
- Identification of a Monoclonal Antibody against Porcine Deltacoronavirus Membrane Protein.International journal of molecular sciences · 2023Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus that caused diarrhea and/or vomiting in neonatal piglets worldwide. Coronaviruses nucleocapsid (N) protein is the most conserved structural protein for viral replication and possesses good antigenicity. In this study, three monoclonal antibodies (mAbs), 3B4, 4D3, and 4E3 identified as subclass IgG2aκ were prepared using the lymphocytic hybridoma technology against PDCoV N protein. Furthermore, the B-cell epitope recognized by mAb 4D3 was mapped by dozens of overlapping truncated recombinant proteins based on the western blotting. The polypeptide
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Registered trials
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