Evidence map›Paper›PMID 36602528›Full record

SynthesisAging2023

A case-control study coupling with meta-analysis elaborates decisive association between

Sui-Lung Su, Yung-Hsun Huang, Yu-Hsuan Chen, Pi-Shao Ko, Wen Su, Chih-Chien Wang, Meng-Chang Lee

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Association between serum insulin-like growth factor 1 and osteoporosis risk in Parkinson's disease: a cross-sectional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sui-Lung SuSchool of Public Health, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Yung-Hsun HuangSchool of Public Health, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Yu-Hsuan ChenSchool of Public Health, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Pi-Shao KoGraduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Wen SuGraduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Chih-Chien WangDepartment of Orthopedics, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, R.O.C.
Meng-Chang LeeSchool of Public Health, National Defense Medical Center, Taipei, Taiwan, R.O.C.
National Defense Medical Center · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis (OP) is prevalent in postmenopausal women. Several studies investigated the association between

objectiveTo investigate whether the

methodsIn case-control study, 95 OP cases and 222 healthy controls were recruited between March 2015 and July 2019. OP was diagnosed based on WHO criteria for diagnosis of OP as T score of bone mineral density (BMD) ≤-2.5; normal, as T score of BMD ≥-1.

resultsIn dominant model of our case-control study, we found nonsignificant association of rs35767 [Adj-OR: 0.95 (95% CI: 0.56-1.60)], rs2288377 [Adj-OR: 1.15 (95% CI: 0.67-1.97)], and rs5742612 [Adj-OR: 1.07 (95% CI: 0.62-1.83)] with OP in postmenopausal females. However, integration of our case-control study and 3 published studies, rs35767 [OR: 1.24 (95% CI: 1.05-1.47)] showed a conclusively risk association with OP in postmenopausal females judged by TSA with 2267 Asians.

conclusionsThis study demonstrates a crucial sample to conclude that

Indexed as

AsianOsteoporosisCase-Control StudiesFemaleGenetic Predisposition to DiseaseHumansInsulin-Like Growth Factor IPolymorphism, Single NucleotidePostmenopauseInsulin-Like Growth Factor Iinsulin-like growth factor-1meta-analysisosteoporosispostmenopausalsingle nucleotide polymorphism

Identifiers

PMID36602528
PMCPMC9876639
OpenAlexW4313520039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.