Evidence map›Paper›PMID 36602309›Full record

ArticlemBio2023

Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2K

Yongli Wang, Minghui Gao, Xiaoying Li, Wenshuai Zhu, Mengchun Zhao, Jiayue Li, Xiaomeng Liu, Letian Cao, Songrui Li, Sumei Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yongli WangCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.
Minghui GaoCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.
Xiaoying LiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China.
Wenshuai ZhuCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.
Mengchun ZhaoCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.
Jiayue LiCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.
Xiaomeng LiuCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.
Letian CaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China.
Songrui LiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China.
Sumei ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China.
Longxian ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China.
Shuhua FanCollege of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People's Republic of China.ORCID 0000-0001-6866-1479
Zhoukou Normal University · CNHenan Agricultural University · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidium parvum has gained much attention as a major cause of diarrhea in the world, particularly in those with compromised immune systems. The data currently available on how the immune system recognizes C. parvum are growing rapidly, but we lack data on the interactions among host major histocompatibility complex (MHC) diversity and parasitic T-cell epitopes. To identify antigenic epitopes in a murine model, we performed systematic profiling of H-2K

Indexed as

CryptosporidiosisCryptosporidiumCryptosporidium parvumAnimalsCD8-Positive T-LymphocytesEpitopes, T-LymphocyteGlycoproteinsHumansImmunodominant EpitopesMiceMice, Inbred C57BLPeptidesReceptors, Antigen, T-CellT-Lymphocytes, CytotoxicEpitopes, T-LymphocyteGlycoproteinsImmunodominant EpitopesPeptidesReceptors, Antigen, T-Cellcell-mediated immunityCryptosporidium parvumMHC IT-cell epitope

Identifiers

PMID36602309
PMCPMC9973275
OpenAlexW4313545150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.