Evidence map›Paper›PMID 36602025›Full record

ArticleeLife2023

Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8.

Nan Wang, Jing He, Xiaoyu Feng, Shengyou Liao, Yi Zhao, Fuchou Tang, Kehkooi Kee

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Direct roles of long non-coding RNAs in transcription activation.Nature structural & molecular biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nan Wang *Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Jing He *Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Xiaoyu Feng *Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Shengyou LiaoKey Laboratory of Intelligent Information Processing, Advanced Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China.
Yi ZhaoKey Laboratory of Intelligent Information Processing, Advanced Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China.
Fuchou TangBiodynamic Optical Imaging Center & Department of Obstetrics and Gynecology, College of Life Sciences, Third Hospital, Peking University, Beijing, China.
Kehkooi KeeCenter for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.ORCID 0000-0001-6926-7203
Tsinghua University · CNChinese Academy of Sciences · CNKing Center · USPeking University · CN

Funding

Ministry of Science and Technology of the People's Republic of China 2018YFA0107703Ministry of Science and Technology of the People's Republic of China 2021YFA0719301National Natural Science Foundation of China 82071597
6 · The paper itself

Abstract

Non-coding RNAs exert diverse functions in many cell types. In addition to transcription factors from coding genes, non-coding RNAs may also play essential roles in shaping and directing the fate of germ cells. The presence of many long non-coding RNAs (lncRNAs) which are specifically expressed in the germ cells during human gonadal development were reported and one divergent lncRNA,

Indexed as

RNA, Long NoncodingCell DifferentiationFemaleGene Expression RegulationGerm CellsHumansLIM-Homeodomain ProteinsMaleTranscription FactorsLIM homeobox protein 8LIM-Homeodomain ProteinsRNA, Long NoncodingTranscription Factorschromosomesdevelopmental biologygene expressiongerm cellhumanhuman gonadal developmentLHX8LncRNAreproductive biologytranscriptional regulation

Identifiers

PMID36602025
PMCPMC9859043
OpenAlexW4313545021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.