Evidence map›Paper›PMID 36602015›Full record

ArticleActa crystallographica. Section C, Structural chemistry2023

A three-step pathway from (2-aminophenyl)chalcones to novel styrylquinoline-chalcone hybrids: synthesis and spectroscopic and structural characterization of three examples.

Diana R Vera, Juan P Mantilla, Alirio Palma, Iván Díaz Costa, Justo Cobo, Christopher Glidewell

Open access · hybridAbstract read
In one paragraph

Article in Acta crystallographica. Section C, Structural chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Diana R VeraLaboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678, Bucaramanga, Colombia.
Juan P MantillaLaboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678, Bucaramanga, Colombia.
Alirio PalmaLaboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678, Bucaramanga, Colombia.
Iván Díaz CostaDepartamento de Química Inorgánica y Orgánica, Universidad de Jaén, 23071 Jaén, Spain.ORCID 0000-0002-7077-9772
Justo CoboDepartamento de Química Inorgánica y Orgánica, Universidad de Jaén, 23071 Jaén, Spain.
Christopher GlidewellSchool of Chemistry, University of St Andrews, Fife KY16 9ST, United Kingdom.ORCID 0000-0001-7621-7538
Industrial University of Santander · COUniversidad de Jaén · ESUniversity of St Andrews · GB

Funding

Vicerrectoría de Investigación y Extensión of the Industrial University of Santander 2680
6 · The paper itself

Abstract

Three new styrylquinoline-chalcone hybrids have been synthesized using a three-step pathway starting with Friedländer cyclocondensation between (2-aminophenyl)chalcones and acetone to give 2-methyl-4-styrylquinolines, followed by selective oxidation to the 2-formyl analogues, and finally Claisen-Schmidt condensation between the formyl intermediates and 1-acetylnaphthalene. All intermediates and the final products have been fully characterized by IR and

Indexed as

ChalconeChalconesCrystallography, X-RayHydrogen BondingQuinolinesChalconeChalconesQuinolinesstyrylquinolinechalconecrystal structurehydrogen bondingmolecular conformationmolecular structureNMR spectroscopyquinolinestyrylquinolinesupramolecular assemblysynthesisπ–π stacking interactions

Identifiers

PMID36602015
PMCPMC9813925
OpenAlexW4311493365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.