ArticleThe British journal of psychiatry : the journal of mental science2023
Childhood trauma, perceived stress and anhedonia in individuals at clinical high risk for psychosis: multigroup mediation analysis.
Article in The British journal of psychiatry : the journal of mental science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Illuminating a joyless life: qualitative, transdiagnostic exploration of anhedonia.BJPsych open · 2026Article
- Stress and synaptic density in psychosis and clinical high risk: evidence from [Translational psychiatry · 2026Article
- The relationship between adverse childhood experiences and depression and anxiety in adolescents: the chain mediating effect of perceived stress and self-hate.Frontiers in psychology · 2026Article
- Anhedonia and depressive symptoms in adolescent university students from china: the mediating role of early perceive stress.BMC public health · 2025Article
- Psychometric Properties of the Chinese Version of the Anhedonia Scale for Adolescents and Identification of the Subpopulation with Prominent Anhedonia.Neuropsychiatric disease and treatment · 2025Article
- Annual Research Review: Puberty and the development of anhedonia - considering childhood adversity and inflammation.Journal of child psychology and psychiatry, and allied disciplines · 2024Review
- Altered hippocampal subfield volumes in major depressive disorder with and without anhedonia.BMC psychiatry · 2023Article
- Negative symptoms in the clinic: we treat what we can describe.The British journal of psychiatry : the journal of mental science · 2023Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundEvidence suggests that both childhood trauma and perceived stress are risk factors for the development of psychosis, as well as negative symptoms such as anhedonia. Previous findings link increases in perceived stress to anhedonia in individuals at clinical high risk for psychosis (CHR) and depression; however, the role of childhood trauma in this relationship has not yet been explored, despite consistent evidence that it is associated with sensitisation to later stress.
aimsTo examine whether perceived stress mediates the relationship between childhood trauma and anhedonia in a group of youth at CHR as well as in controls (groups with depression and with no diagnosed mental health concerns).
methodThe study used multigroup mediation to examine the indirect effects of childhood trauma on anhedonia via perceived stress in CHR (
resultsPerceived stress mediated the relationship between childhood trauma and consummatory anhedonia regardless of group status. Perceived stress mediated the relationship between childhood trauma and anticipatory anhedonia for the CHR and depression groups, but not for non-psychiatric controls. Further, groups differed in the magnitude of this relationship, with the effects trending towards stronger for those in the CHR group.
conclusionsOur findings suggest a potential transdiagnostic pathway through which childhood trauma contributes to anhedonia across severe mental illness.
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