Evidence map›Paper›PMID 36601694›Full record

ArticleBrain and behavior2023

Whole-brain DTI parameters associated with tau protein and hippocampal volume in Alzheimer's disease.

Thamires Naela Cardoso Magalhães, Raphael Fernandes Casseb, Christian Luiz Baptista Gerbelli, Luciana Ramalho Pimentel-Siva, Mateus Henrique Nogueira, Camila Vieira Ligo Teixeira, Ana Flávia Mac Knight Carletti, Thiago Junqueira Ribeiro de Rezende, Helena Passarelli Giroud Joaquim, Leda Leme Talib and 3 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Thamires Naela Cardoso MagalhãesDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Raphael Fernandes CassebDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Christian Luiz Baptista GerbelliDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Luciana Ramalho Pimentel-SivaDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Mateus Henrique NogueiraDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Camila Vieira Ligo TeixeiraBrazilian Institute of Neuroscience and Neurotechnology, São Paulo, Brazil.
Ana Flávia Mac Knight CarlettiDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Thiago Junqueira Ribeiro de RezendeDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Helena Passarelli Giroud JoaquimLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo (USP), São Paulo, Brazil.
Leda Leme TalibLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo (USP), São Paulo, Brazil.
Orestes Vicente ForlenzaLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo (USP), São Paulo, Brazil.
Fernando CendesDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Marcio Luiz Figueredo BalthazarDepartment of Neurology and Neuroimaging Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade de São Paulo · BRBrazilian Institute of Neuroscience and Neurotechnology · BRNational Institute on Aging · US

Funding

São Paulo Research Foundation (FAPESP) 2011/17092-0São Paulo Research Foundation (FAPESP) 2017/01286-6São Paulo Research Foundation (FAPESP) 2017/13906-9São Paulo Research Foundation (FAPESP) 2018/15571-7
6 · The paper itself

Abstract

The causes of the neurodegenerative processes in Alzheimer's disease (AD) are not completely known. Recent studies have shown that white matter (WM) damage could be more severe and widespread than whole-brain cortical atrophy and that such damage may appear even before the damage to the gray matter (GM). In AD, Amyloid-beta (Aβ

Indexed as

Alzheimer DiseaseCognitive DysfunctionAtrophyBiomarkersBrainDiffusion Tensor ImagingHippocampusHumanstau ProteinsBiomarkerstau ProteinsAlzheimer's disease pathologybiomarkersCSF proteinsDTI measureswhite matter damage

Identifiers

PMID36601694
PMCPMC9927845
OpenAlexW4313500687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.