Evidence map›Paper›PMID 36601536›Full record

ArticleFrontiers in cell and developmental biology2022

Endogenous Bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis.

Caden G Bonzerato, Katherine R Keller, Jacqualyn J Schulman, Xiaokong Gao, Laura M Szczesniak, Richard J H Wojcikiewicz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Phosphorylation of Bok at Ser-8 blocks its ability to suppress IPCell communication and signaling : CCS · 2025
    Article
  4. Bok: real killer or bystander with non-apoptotic roles?Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Caden G BonzeratoDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, United States.
Katherine R KellerDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, United States.
Jacqualyn J SchulmanDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, United States.
Xiaokong GaoDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, United States.
Laura M SzczesniakDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, United States.
Richard J H WojcikiewiczDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, United States.
SUNY Upstate Medical University · US

Funding

Significance of the novel Bok-IP3 receptor interactionR01GM121621 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI WOJCIKIEWICZ, RICHARD J H · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM121621
6 · The paper itself

Abstract

Controversy surrounds the cellular role of the Bcl-2 family protein Bok. On one hand, it has been shown that all endogenous Bok is bound to inositol 1,4,5-trisphosphate receptors (IP

Indexed as

apoptosisB cell Lymphoma 2 (Bcl-2) familyBcl-2 related ovarian killerER membraneinositol 1,4,5-trisphosphate receptormyeloid-cell leukemia 1ubiquitin proteasomal pathway

Identifiers

PMID36601536
PMCPMC9806350
OpenAlexW4313396401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.