Evidence map›Paper›PMID 36601515›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2022

Noscapine hydrochloride (benzyl-isoquinoline alkaloid) effectively prevents protein denaturation through reduction of IL-6, NF-kB, COX-2, Prostaglandin-E2 in rheumatic rats.

Shanila Akhter, Hafiz Muhammad Irfan, Alamgeer, Aman Ullah, Shah Jahan, Muhammad Roman, Muhammad Bilal Latif, Zaid Mustafa, Farooq M Almutairi, Yusuf S Althobaiti

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Saudi journal of biological sciences · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Shanila AkhterCollege of Pharmacy, University of Sargodha, Sargodha, 40100, Pakistan.
Hafiz Muhammad IrfanCollege of Pharmacy, University of Sargodha, Sargodha, 40100, Pakistan.
AlamgeerDepartment of Pharmacology, Punjab University College of Pharmacy, University of the Punjab, Lahore, 54590, Pakistan.
Aman UllahCollege of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, 44000, Pakistan.
Shah JahanDepartment of Immunology, University of Health Sciences, Lahore, 54600, Pakistan.
Muhammad RomanDepartment of Immunology, University of Health Sciences, Lahore, 54600, Pakistan.
Muhammad Bilal LatifDepartment of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, 30322, USA.
Zaid MustafaDepartment of Agricultural Sciences, Allama Iqbal Open University Islamabad, 44000, Pakistan.
Farooq M AlmutairiDepartment of Clinical Laboratories Sciences, College of Applied Medical Sciences, University of Hafr AlBatin, Hafr AlBatin, 39524, Saudi Arabia.
Yusuf S AlthobaitiDepartment of Pharmacology and Toxicology, College of Pharmacy, Taif University, 21944, Saudi Arabia.
University of Health Sciences Lahore · PKUniversity of Sargodha · PKAllama Iqbal Open University · PKEmory University · USShifa Tameer-e-Millat University · PKTaif University · SAUniversity of Hafr Al-Batin · SAUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noscapine hydrochloride (benzyl-isoquinoline antitussive alkaloid) is an opium derivative and generally used as a cough suppressant

Indexed as

AntioxidantBenzylisoquinoline alkaloidsPro- and anti-inflammatory cytokinesProtein denaturation

Identifiers

PMID36601515
PMCPMC9805980
OpenAlexW4306812114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.