Evidence map›Paper›PMID 36601453›Full record

ArticleRadiology. Cardiothoracic imaging2022

Airway Detection in COPD at Low-Dose CT Using Deep Learning and Multiparametric Freeze and Grow.

Syed Ahmed Nadeem, Alejandro P Comellas, Eric A Hoffman, Punam K Saha

Open access · greenAbstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Article
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  7. A Survey on Artificial Intelligence in Pulmonary Imaging.Wiley interdisciplinary reviews. Data mining and knowledge discovery
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Syed Ahmed NadeemDepartments of Radiology (S.A.N., E.A.H., P.K.S.) and Internal Medicine (A.P.C., E.A.H.), Carver College of Medicine, and Departments of Biomedical Engineering (E.A.H.) and Electrical and Computer Engineering (P.K.S.), College of Engineering, The University of Iowa, 4312 Seamans Center, Iowa City, IA 52242.ORCID https://orcid.org/0000-0002-5933-3825
Alejandro P ComellasDepartments of Radiology (S.A.N., E.A.H., P.K.S.) and Internal Medicine (A.P.C., E.A.H.), Carver College of Medicine, and Departments of Biomedical Engineering (E.A.H.) and Electrical and Computer Engineering (P.K.S.), College of Engineering, The University of Iowa, 4312 Seamans Center, Iowa City, IA 52242.ORCID https://orcid.org/0000-0003-1521-7520
Eric A HoffmanDepartments of Radiology (S.A.N., E.A.H., P.K.S.) and Internal Medicine (A.P.C., E.A.H.), Carver College of Medicine, and Departments of Biomedical Engineering (E.A.H.) and Electrical and Computer Engineering (P.K.S.), College of Engineering, The University of Iowa, 4312 Seamans Center, Iowa City, IA 52242.ORCID https://orcid.org/0000-0001-8456-9437
Punam K SahaDepartments of Radiology (S.A.N., E.A.H., P.K.S.) and Internal Medicine (A.P.C., E.A.H.), Carver College of Medicine, and Departments of Biomedical Engineering (E.A.H.) and Electrical and Computer Engineering (P.K.S.), College of Engineering, The University of Iowa, 4312 Seamans Center, Iowa City, IA 52242.ORCID https://orcid.org/0000-0003-1576-118X
University of Iowa · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Multi-center Structural & Functional Quantitative CT Pulmonary PhenotypingR01HL112986 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2012 to 2016
$4.6M
CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPDR01HL142042 · NHLBI · UNIVERSITY OF IOWA · PI SAHA, PUNAM K. · 2018 to 2022
$3.5M
NHLBI NIH HHS R01 HL112986NHLBI NIH HHS R01 HL142042NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

Purpose: To present and validate a fully automated airway detection method at low-dose CT in patients with chronic obstructive pulmonary disease (COPD). Materials and Methods: In this retrospective study, deep learning (DL) and freeze-and-grow (FG) methods were optimized and applied to automatically detect airways at low-dose CT. Four data sets were used: two data sets consisting of matching standard- and low-dose CT scans from the Genetic Epidemiology of COPD (COPDGene) phase II (2014-2017) cohort ( Results: At low-dose CT, 56 294 of 62 480 (90.1%) airways of the reference total airway count (TAC) and 32 109 of 37 864 (84.8%) airways of the peripheral TAC (TAC Conclusion: A low-cost, automated CT-based airway detection method was suitable for investigation of airway phenotypes at low-dose CT.

Indexed as

AirwayAirway CountAirway DetectionChronic Obstructive Pulmonary DiseaseCTDeep LearningGeneralizabilityLow-Dose CTLungSegmentationThorax

Identifiers

PMID36601453
PMCPMC9806731
OpenAlexW4311064776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.