Evidence map›Paper›PMID 36601409›Full record

ArticleMolecular vision2022

Lipoxin A4 alleviates inflammation in

Xudong Peng, Xiaojia Zhu, Junjie Luan, Jing Lin, Yingxue Zhang, Qian Wang, Guiqiu Zhao

Open access · greenAbstract read
In one paragraph

Article in Molecular vision, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xudong PengDepartment of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Xiaojia ZhuTianjin Hospital, Tianjin, China.
Junjie LuanDepartment of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Jing LinDepartment of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Yingxue ZhangDepartment of Biochemistry, Microbiology and Immunology, Wayne State University School of Medicine, Detroit, MI.
Qian WangDepartment of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Guiqiu ZhaoDepartment of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Qingdao University · CNTianjin Hospital · CNWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the therapeutic effect of lipoxin A4 (LXA4) on Methods: The cell counting kit-8 (CCK-8) was performed in HCECs to evaluate the toxicity of LXA4. A cell scratch test was used to assess the impact of LXA4 on the migration of HCECs. Enzyme-linked immunosorbent assay (ELISA), quantitative real-time polymerase chain reaction (qRT-PCR), and western blot were applied to examine the expression of inflammatory mediators in Results: LXA4 at 0-10 nmol·L Conclusions: LXA4 plays a protective role in

Indexed as

Aspergillus fumigatusHeme Oxygenase-1Epithelial CellsHumansInflammationInflammation MediatorsLipoxinsNF-E2-Related Factor 2Signal TransductionHeme Oxygenase-1Inflammation Mediatorslipoxin A4LipoxinsNF-E2-Related Factor 2

Identifiers

PMID36601409
PMCPMC9767844
OpenAlexW4313546545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.