ArticleEuropean urology open science2023
Role of the Prostate Imaging Quality PI-QUAL Score for Prostate Magnetic Resonance Image Quality in Pathological Upstaging After Radical Prostatectomy: A Multicentre European Study.
Article in European urology open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- The clinical utility of prostate MRI before biopsy.Nature reviews. Urology · 2026Review
- Diagnostic accuracy of a 'stage-gated' approach for reporting prostate screening MRI: "Is less more?"European radiology · 2026Article
- Prostate MRI quality improvement: a Roadmap from the ESUR Prostate MRI Working Group.European radiology · 2026Review
- ESR Essentials: MRI-based T-staging in prostate cancer-practice recommendations by the European Society of Urogenital Radiology.European radiology · 2026Review
- Multi-reader evaluation of the prostate imaging quality score system version 2 (PI-QUAL V2) and its clinical application.European radiology · 2025Article
- Imaging in focal therapy: advanced ultrasound imaging and mpMRI-a comprehensive review.Prostate cancer and prostatic diseases · 2025Review
- Predicting ADC map quality from T2-weighted MRI: A deep learning approach for early quality assessment to assist point-of-care.European journal of radiology · 2025Article
- Impact of the PI-QUAL MRI quality score on histopathological up-staging from MRI fusion biopsy to final prostatectomy specimen.World journal of urology · 2025Article
- PI-QUAL version 2 image quality categorisation and inter-reader agreement compared to version 1.European radiology · 2025Article
- Biopsy strategies in the era of mpMRI: a comprehensive review.Prostate cancer and prostatic diseases · 2025Review
- Performing liver imaging at a high level: quality and adequacy in LI-RADS.Abdominal radiology (New York) · 2025Review
- Deep learning for quality assessment of axial T2-weighted prostate MRI: a tool to reduce unnecessary rescanning.European radiology experimental · 2025Article
- MRI characteristics predict risk of pathological upgrade in patients with ISUP grade group 1 prostate cancer.European radiology · 2025Article
- Intraoperative technologies to assess margin status during radical prostatectomy - a narrative review.Prostate cancer and prostatic diseases · 2025Review
- High-resolution Diffusion-weighted Imaging of the Prostate Using Multiplexed Sensitivity-encoding: Comparison with the Conventional and Reduced Field-of-view Techniques.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Emerging and anticipated innovations in prostate cancer MRI and their impact on patient care.Abdominal radiology (New York) · 2024Review
- Deep learning-based image quality assessment: impact on detection accuracy of prostate cancer extraprostatic extension on MRI.Abdominal radiology (New York) · 2024Article
- Expect the unexpected: investigating discordant prostate MRI and biopsy results.European radiology · 2024Article
- Self-supervised multicontrast super-resolution for diffusion-weighted prostate MRI.Magnetic resonance in medicine · 2024Article
- The impact of prostate volume estimation on the risk-adapted biopsy decision based on prostate-specific antigen density and magnetic resonance imaging score.World journal of urology · 2024Article
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Increasing use of multiparametric magnetic resonance imaging (mpMRI) has come with heterogeneity in image quality. The Prostate Imaging Quality (PI-QUAL) score is under scrutiny to assess its usefulness in predicting clinical outcomes. Objective: To compare upstaging of localized disease on mpMRI (mrT2) to locally invasive disease in radical prostatectomy (RP) specimens (≥pT3a) in relation to PI-QUAL. Design setting and participants: Patients treated with RP between 2015 and 2020 who underwent 1.5-3-T mpMRI within 6 mo before surgery and had systematic and mpMRI-US targeted biopsies were included. mpMRI scans were retrospectively assigned a PI-QUAL score, and prospectively acquired Prostate Imaging-Recording and Data System (PI-RADS) scores (version 2.0 or 2.1) were used. PI-QUAL scores were categorized as nondiagnostic (PI-QUAL <3), sufficient (PI-QUAL 3), or optimal (PI-QUAL >3). Outcome measurements and statistical analysis: We assessed the relationship between the PI-QUAL score and upstaging using multivariate logistic regression. mpMRI, clinical, and pathological findings were compared using χ Results and limitations: We identified 351 patients, of whom 40 (11.4%) had PI-QUAL <3, 57 (16.3%) had PI-QUAL 3, and 254 (72.3%) had PI-QUAL >3 scores. The distribution of PI-QUAL <3 (0-33.6%; Conclusions: In comparison to PI-QUAL ≥3, PI-QUAL <3 was significantly associated with a higher rate of upstaging from organ-confined disease on mpMRI to locally advanced disease on pathology, lower detection rates for PI-RADS 5 lesions and extraprostatic extension, and a lower number of suspicious lesions. Patient summary: Poor image quality for magnetic resonance imaging (MRI) scans of the prostate is associated with underestimation of the stage of prostate cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.