ReviewTherapeutic advances in urology
Multiparametric ultrasound of prostate: role in prostate cancer diagnosis.
Review in Therapeutic advances in urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Prostate cancer-multiparametric MRI and alternative approaches in intervention and therapy planning].Urologie (Heidelberg, Germany) · 2023Pooled it
- Focal Therapy for Prostate Cancer: State of the Art, Physical Principles, Potentials, and Challenges.Cancers · 2026Review
- Primary healthcare-friendly prostate cancer prediction model using routine clinical parameters: a multicenter study.Frontiers in oncology · 2026Article
- Emerging imaging modalities for the diagnosis of malignant lesions of the male reproductive tract in companion animals.Animal reproduction · 2026Review
- Decade-long landscape of transrectal ultrasound (TRUS) in prostate cancer research: trends, collaborations, and emerging frontiers.Journal of ultrasound · 2025Article
- Three-Dimensional Shear-Wave Viscoelastographic Estimation by System Identification for Prostate Cancer Localization.Ultrasound in medicine & biology · 2025Article
- Emerging tools for the early detection of prostate cancer.BJUI compass · 2025Review
- Developments in Ultrasound-Based Imaging for Prostate Cancer Detection.The Prostate · 2025Review
- Time-Intensity Curve parametric imaging as a novel quantitative biomarker: enhancing diagnostic accuracy and inter-rater reliability in prostate cancer ultrasound.Frontiers in oncology · 2025Article
- Advances in imaging and artificial intelligence for precision diagnosis and biopsy guidance in prostate cancer.Frontiers in oncology · 2025Review
- Diagnostic utility of serum prostate-specific antigen and circulating inflammatory markers for differentiating prostate cancer from benign prostatic hyperplasia.American journal of cancer research · 2025Article
- Diagnostic performance of multiple ultrasonic modalities for prostate cancer.Clinics (Sao Paulo, Brazil) · 2025Article
- Review
- Do we need MRI in all biopsy naïve patients? A multicenter cohort analysis.World journal of urology · 2024Article
- Advances in radiology and pathology of prostate cancer: a review for the pathologist.Pathologica · 2024Review
- Diagnostic accuracy of multiparametric ultrasound in the diagnosis of prostate cancer: systematic review and meta-analysis.Insights into imaging · 2023Review
- The Diagnostic Performance of Multiparametric Ultrasound in the Qualitative Assessment of Inconclusive Cervical Lymph Nodes.Cancers · 2023Article
- Contemporary Review of Multimodality Imaging of the Prostate Gland.Diagnostics (Basel, Switzerland) · 2023Review
- Development and validation of a nomogram for predicting prostate cancer based on combining contrast-enhanced transrectal ultrasound and biparametric MRI imaging.Frontiers in oncology · 2023Article
- Micro-ultrasound versus mpMRI for targeted prostate biopsy: A systematic review, meta-analysis, and clinical integration.Therapeutic advances in urologyArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent advances in ultrasonography (US) technology established modalities, such as Doppler-US, HistoScanning, contrast-enhanced ultrasonography (CEUS), elastography, and micro-ultrasound. The early results of these US modalities have been promising, although there are limitations including the need for specialized equipment, inconsistent results, lack of standardizations, and external validation. In this review, we identified studies evaluating multiparametric ultrasonography (mpUS), the combination of multiple US modalities, for prostate cancer (PCa) diagnosis. In the past 5 years, a growing number of studies have shown that use of mpUS resulted in high PCa and clinically significant prostate cancer (CSPCa) detection performance using radical prostatectomy histology as the reference standard. Recent studies have demonstrated the role mpUS in improving detection of CSPCa and guidance for prostate biopsy and therapy. Furthermore, some aspects including lower costs, real-time imaging, applicability for some patients who have contraindication for magnetic resonance imaging (MRI) and availability in the office setting are clear advantages of mpUS. Interobserver agreement of mpUS was overall low; however, this limitation can be improved using standardized and objective evaluation systems such as the machine learning model. Whether mpUS outperforms MRI is unclear. Multicenter randomized controlled trials directly comparing mpUS and multiparametric MRI are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.