Evidence map›Paper›PMID 36600999›Full record

ArticleJournal of tissue engineering

Engineering transplantable human lymphatic and blood capillary networks in a porous scaffold.

Anne M Kong, Shiang Y Lim, Jason A Palmer, Amanda Rixon, Yi-Wen Gerrand, Kiryu K Yap, Wayne A Morrison, Geraldine M Mitchell

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Methods for Assessing Scaffold Vascularization with Human Endothelial Cells.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Anne M KongO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Shiang Y LimO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Jason A PalmerO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Amanda RixonExperimental Medical and Surgical Unit, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.
Yi-Wen GerrandO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Kiryu K YapO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Wayne A MorrisonO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Geraldine M MitchellO'Brien Institute Department of St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.ORCID https://orcid.org/0000-0003-1092-8630
The University of Melbourne · AUO'Brien Institute · AUSt Vincent's Hospital Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to a relative paucity of studies on human lymphatic assembly in vitro and subsequent in vivo transplantation, capillary formation and survival of primary human lymphatic (hLEC) and blood endothelial cells (hBEC) ± primary human vascular smooth muscle cells (hvSMC) were evaluated and compared in vitro and in vivo. hLEC ± hvSMC or hBEC ± hvSMC were seeded in a 3D porous scaffold in vitro, and capillary percent vascular volume (PVV) and vascular density (VD)/mm

Indexed as

capillary networks in vitro 3D co-culturein vivo transplantationprimary human blood endothelial cellsPrimary human lymphatic endothelial cells

Identifiers

PMID36600999
PMCPMC9806376
OpenAlexW4313153092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.