ArticleFrontiers in public health2022
The dose-response relationship between BMI and hypertension based on restricted cubic spline functions in children and adolescents: A cross-sectional study.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Secular trends in society-, school-, and individual-level factors related to physical activity and their associations with elevated blood pressure among 0.6 million children and adolescents.Chinese medical journal · 2026Article
- Associations of growth trajectories from birth to two years of age with adolescent blood pressure: the mediating role of current BMI in the follow-up of an antenatal micronutrient supplementation trial.European journal of pediatrics · 2026Observational
- Nonlinear dose-response relationships between psychological and behavioral factors and training quality among firefighters: a restricted cubic spline analysis.Frontiers in public health · 2026Article
- The relationship between hypertension, anemia, and BMI in women of reproductive age: evidence from a nationwide health study.BMC cardiovascular disorders · 2025Article
- The Prevalence of Hypertension Among Children and Antihypertensive Use: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2025Article
- Association of 24 Conventional and Unconventional Anthropometric Indicators with Pre-Hypertension or Hypertension: A Population-Based Cross-Sectional Study in Chinese Population.Vascular health and risk management · 2025Article
- Interaction of serum uric acid with overweight on hypertension: findings from the China Health and Nutrition Survey.BMC cardiovascular disorders · 2024Article
- Dose-response relationship between body mass index and hypertension: A cross-sectional study from Eastern China.Preventive medicine reports · 2024Article
- Daily Physical Activity Does Not Contribute to Differences in Muscle Oxidative Capacity Between Overweight and Obesity.Endocrinology, diabetes & metabolism · 2024Article
- Prevalence of Systemic Hypertension and the Effects of Cerebral Revascularization in Patients With Moyamoya Disease.Stroke (Hoboken, N.J.) · 2024Article
- Perfluoroalkyl substances in umbilical cord blood and blood pressure in offspring: a prospective cohort study.Environmental health : a global access science source · 2023Article
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7 authors.
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Abstract
Background: A high body mass index (BMI) is a major risk factor for hypertension. The purpose of this study was to investigate the association between the BMI and hypertension in children and adolescents. Methods: We analyzed physical examination data from 29,810 students aged 6-14 years old. A restricted cubic spline (RCS) function was used to investigate the dose-response relationship between the BMI and hypertension. Results: The prevalence of hypertension was 9.91%, followed by 11.71% in males and 7.9% in females, respectively. Compared to the normal weight group, the odds risk (OR) for hypertension in the overweight group was 1.729, and the OR for hypertension in the obesity group was 3.089. After adjusting for potential confounders, the adjusted ORs were 1.620 [95% confidence interval (CI): 1.457-1.800] in the overweight group and 3.092 (95% CI: 2.824-3.385) in the obesity group. According to the multivariate RCS regression analysis, there was a significant non-linear dose-response association between the BMI and the risk of hypertension (all P-values for non-linear < 0.001). Conclusion: The dose-response relationship analysis showed that the association strength of hypertension increased non-linearly along with the continuous change of BMI in children and adolescents.
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