ArticleBMJ open2022
Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Socioeconomic differences in prevalence and patterns of non-communicable disease multimorbidity and its impact on depression in rural Southwest China.Preventive medicine reports · 2025Article
- Investigation of multimorbidity patterns and association rules in patients with type 2 diabetes mellitus using association rules mining algorithm.Scientific reports · 2025Article
- Prevalence of multimorbidity among urban-rural older adults in Mongolia: a cross-sectional study.BMC public health · 2025Article
- Uncovering bridging diseases in complex multimorbidity pathways: A network science approach.PloS one · 2025Article
- Examining the relationships between patients' multimorbidity trajectories and prognostic outcomes after the initial hip fracture.Scientific reports · 2024Article
- Multimorbidity in Atherosclerotic Cardiovascular Disease and Its Associations With Adverse Cardiovascular Events and Healthcare Costs: A Real-World Evidence Study.Journal of health economics and outcomes research · 2024Article
- Detecting Multimorbidity Patterns with Association Rule Mining in Patients with Alzheimer's Disease and Related Dementias.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024Article
- Multimorbidity combinations among older adults in Singapore: A cross-sectional study using polyclinic data.Journal of multimorbidity and comorbidityArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.
designA cross-sectional study.
settingNational Health and Nutrition Examination Surveys database.
participants12 576 patients. PRIMARY AND SECONDARY OUTCOME MEASURES: The prevalence and patterns of multimorbidity.
resultsHigh cholesterol had the highest prevalence in all population (33.4 (95% CI: 32.0 to 34.9)) and males. In females <65 years, the most prevalent disease was sleep disorder (32.1 (95% CI: 29.6 to 34.5)) while in females ≥65 years, hypertension was the most prevalent disease (63.9 (95% CI: 59.9 to 67.9)). Hypertension and high cholesterol were associated with the highest support (occur together most frequently) in all population regardless of genders. Hypertension displayed the highest betweenness centrality (mediating role in the network) followed by high cholesterol and arthritis in all population. For males aged <65 years, hypertension and high cholesterol presented the highest betweenness centrality. In males ≥65 years, hypertension, high cholesterol and arthritis were the top three diseases of degree centrality (direct association with other conditions). As for females ≥65 years, hypertension showed the highest betweenness centrality followed by high cholesterol and arthritis. The associations of hypertension, arthritis and one other item with high cholesterol presented the highest support in all population. In males, the associations of depression, hypertension with sleep disorders had the highest lift (the chance of co-occurrence of the conditions and significant association). Among females, the associations of depression, arthritis with sleep disorders had the highest lift.
conclusionHypertension and high cholesterol were prevalent in all population, regardless of females and males. Hypertension and high cholesterol, arthritis and hypertension, and diabetes and hypertension were more likely to coexist. The findings of this study might help make plans for the management and primary care of people with one or more diseases.
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