Evidence map›Paper›PMID 36600182›Full record

ArticleAnnals of the rheumatic diseases2023

Alterations in the cutaneous microbiome of patients with psoriasis and psoriatic arthritis reveal similarities between non-lesional and lesional skin.

Alba Boix-Amorós, Michelle H Badri, Julia Manasson, Rebecca B Blank, Rebecca H Haberman, Andrea L Neimann, Parvathy V Girija, Anthony Jimenez Hernandez, Adriana Heguy, Sergei B Koralov and 3 more

Open access · greenAbstract read
In one paragraph

Article in Annals of the rheumatic diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Materials today. Bio · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Skin Microbiome in Health and Disease: Mechanisms and Emerging Therapeutic Strategies.Clinical, cosmetic and investigational dermatology · 2025
    Review
  11. Article
  12. Frontiers in immunology · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Lyme Arthritis: A 50-Year Journey.The Journal of infectious diseases · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Alba Boix-AmorósGenetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0003-2776-6500
Michelle H BadriDepartment of Biology, New York University, New York, New York, USA.
Julia ManassonDivision of Rheumatology, Department of Medicine and Psoriatic Arthritis Center, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0003-3448-5520
Rebecca B BlankDivision of Rheumatology, Department of Medicine and Psoriatic Arthritis Center, New York University Grossman School of Medicine, New York, New York, USA.
Rebecca H HabermanDivision of Rheumatology, Department of Medicine and Psoriatic Arthritis Center, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-7119-8136
Andrea L NeimannRonald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, New York, USA.
Parvathy V GirijaDivision of Rheumatology, Department of Medicine and Psoriatic Arthritis Center, New York University Grossman School of Medicine, New York, New York, USA.
Anthony Jimenez HernandezDivision of Rheumatology, Department of Medicine and Psoriatic Arthritis Center, New York University Grossman School of Medicine, New York, New York, USA.
Adriana HeguyNYU Langone Health Genome Technology Center, Department of Pathology, New York University Grossman School of Medicine, New York, New York, USA.
Sergei B KoralovDepartment of Pathology, New York University Grossman School of Medicine, New York, New York, USA.
Richard BonneauDepartment of Biology, New York University, New York, New York, USA.
Jose C ClementeGenetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Jose U ScherDivision of Rheumatology, Department of Medicine and Psoriatic Arthritis Center, New York University Grossman School of Medicine, New York, New York, USA jose.scher@nyulangone.org.ORCID 0000-0002-1072-6994
New York University · USIcahn School of Medicine at Mount Sinai · USSimons Foundation · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Micro-TeACH (Microbiome Technology and Analytic Center Hub)UC2AR081034 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jose C Clemente, ADRIANA HEGUY · 2022 to 2026
$4.6M
Employing the gut microbiome to accelerate effective initiation of rheumatoid arthritis therapyR01AR074500 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Renuka Rajendra Nayak, Jose U. Scher · 2019 to 2026
$4.1M
Translational Basic and Clinical Research Training in RheumatologyT32AR069515 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jill P Buyon, Jose U. Scher · 2017 to 2026
$2.9M
NCI NIH HHS P30 CA016087NIAMS NIH HHS R01 AR074500NIAMS NIH HHS T32 AR069515NIAMS NIH HHS UC2 AR081034
6 · The paper itself

Abstract

objectivesTo investigate the cutaneous microbiome spanning the entire psoriatic disease spectrum, and to evaluate distinguishing features of psoriasis (PsO) and psoriatic arthritis (PsA).

methodsSkin swabs were collected from upper and lower extremities of healthy individuals and patients with PsO and PsA. Psoriatic patients contributed both lesional (L) and contralateral non-lesional (NL) samples. Microbiota were analysed using 16S rRNA sequencing.

resultsCompared with healthy skin, alpha diversity in psoriatic NL and L skin was significantly reduced (p<0.05) and samples clustered separately in plots of beta diversity (p<0.05).

conclusionsThese findings show differences in diversity, bacterial composition and microbe-microbe interactions between healthy and psoriatic skin, both L and NL. We further identified bacterial biomarkers that differentiate disease phenotypes, which could potentially aid in predicting the transition from PsO to PsA.

Indexed as

Arthritis, PsoriaticMicrobiotaPsoriasisBacteriaBiomarkersHumansRNA, Ribosomal, 16SSkinBiomarkersRNA, Ribosomal, 16SArthritis, PsoriaticAutoimmune DiseasesEpidemiology

Identifiers

PMID36600182
PMCPMC11131958
OpenAlexW4312133058

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.