Evidence map›Paper›PMID 36599936›Full record

ReviewNature reviews. Genetics2023

Current advances in primate genomics: novel approaches for understanding evolution and disease.

David Juan, Gabriel Santpere, Joanna L Kelley, Omar E Cornejo, Tomas Marques-Bonet

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  5. Accelerated cell-type-specific regulatory evolution of the human brain.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David Juan *Institute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain.ORCID 0000-0003-1912-9667
Gabriel Santpere *Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), MELIS, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.ORCID 0000-0001-5909-8637
Joanna L KelleySchool of Biological Sciences, Washington State University, Pullman, WA, USA.ORCID 0000-0002-7731-605X
Omar E CornejoSchool of Biological Sciences, Washington State University, Pullman, WA, USA. omcornej@ucsc.edu.ORCID 0000-0003-4076-4227
Tomas Marques-BonetInstitute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain. tomas.marques@upf.edu.ORCID 0000-0002-5597-3075

Funding

Identification of Genetic and Molecular Bases of Derived Phenotypes in Primate Brain DevelopmentR01HG010898 · NHGRI · YALE UNIVERSITY · PI SANTPERE BARO, GABRIEL, SESTAN, NENAD · 2020 to 2023
$2.2M
NHGRI NIH HHS R01 HG010898
6 · The paper itself

Abstract

Primate genomics holds the key to understanding fundamental aspects of human evolution and disease. However, genetic diversity and functional genomics data sets are currently available for only a few of the more than 500 extant primate species. Concerted efforts are under way to characterize primate genomes, genetic polymorphism and divergence, and functional landscapes across the primate phylogeny. The resulting data sets will enable the connection of genotypes to phenotypes and provide new insight into aspects of the genetics of primate traits, including human diseases. In this Review, we describe the existing genome assemblies as well as genetic variation and functional genomic data sets. We highlight some of the challenges with sample acquisition. Finally, we explore how technological advances in single-cell functional genomics and induced pluripotent stem cell-derived organoids will facilitate our understanding of the molecular foundations of primate biology.

Indexed as

Evolution, MolecularGenomicsAnimalsGenetic VariationGenomeHumansPhylogenyPrimates

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.