ArticleNature communications2023
Cerebro-cerebellar networks facilitate learning through feedback decoupling.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 42 citations in OpenAlex.
- Personalized high-intensity temporal interference stimulation decouples cerebellar networks to enhance implicit learning.Journal of neuroengineering and rehabilitation · 2026Trial
- Bilateral effect of acupuncture on cerebrum and cerebellum in ischaemic stroke patients with hemiparesis: a randomised clinical and neuroimaging trial.Stroke and vascular neurology · 2024Trial
- From metabolic intermediary to neurotransmitter: purinergic signaling in neurophysiology and vulnerability of brain circuits.Bioscience reports · 2026Review
- Brain-AI convergence: Generative world models and hierarchical attention for human intelligence.Patterns (New York, N.Y.) · 2026Review
- Cerebellum-inspired neural network of supervised learning with tensor-based sparse coding for multi-class classification.PLoS computational biology · 2026Article
- The Cerebellar Connectome.Cerebellum (London, England) · 2026Article
- Motor-related reorganization in left inferior frontal gyrus after subcortical stroke: neurochemical basis and response to targeted neuromodulation.BMC medicine · 2026Article
- Contextual inference through flexible integration of environmental features and behavioural outcomes.PLoS computational biology · 2026Article
- Immersive Rehabilitation Therapy (MoveR) Improves Postural and Visuo-Attentional Skills in Children with ADHD: A Clinical Study.Life (Basel, Switzerland) · 2026Article
- Article
- Cognitive functioning in multiple sclerosis with focus on brainstem volume.Acta neurologica Belgica · 2026Article
- Artificial intelligence as a surrogate brain: bridging neural dynamical models and data.National science review · 2026Review
- Temporal dynamics between the whisker sensorimotor cortex and the olivocerebellar module in awake mice.Frontiers in cellular neuroscience · 2026Article
- Stage-dependent cerebrocerebellar communication during sensorimotor processing.Nature communications · 2025Article
- Synergistic Reinforcement Learning by Cooperation of the Cerebellum and Basal Ganglia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A wearable obstacle avoidance device for visually impaired individuals with cross-modal learning.Nature communications · 2025Article
- Cerebellar output shapes cortical preparatory activity during motor adaptation.Nature communications · 2025Article
- Cerebellar output shapes cortical preparatory activity during motor adaptation.bioRxiv : the preprint server for biology · 2025Article
- A neural implementation model of feedback-based motor learning.Nature communications · 2025Article
- Emergent Aspects of the Integration of Sensory and Motor Functions.Brain sciences · 2025Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Behavioural feedback is critical for learning in the cerebral cortex. However, such feedback is often not readily available. How the cerebral cortex learns efficiently despite the sparse nature of feedback remains unclear. Inspired by recent deep learning algorithms, we introduce a systems-level computational model of cerebro-cerebellar interactions. In this model a cerebral recurrent network receives feedback predictions from a cerebellar network, thereby decoupling learning in cerebral networks from future feedback. When trained in a simple sensorimotor task the model shows faster learning and reduced dysmetria-like behaviours, in line with the widely observed functional impact of the cerebellum. Next, we demonstrate that these results generalise to more complex motor and cognitive tasks. Finally, the model makes several experimentally testable predictions regarding cerebro-cerebellar task-specific representations over learning, task-specific benefits of cerebellar predictions and the differential impact of cerebellar and inferior olive lesions. Overall, our work offers a theoretical framework of cerebro-cerebellar networks as feedback decoupling machines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.