Evidence map›Paper›PMID 36599494›Full record

ArticleBMJ case reports2023

Management of basal cell carcinoma with pulmonary metastasis.

Samuel Achilles Fordham, Emily Ximin Shao, Leith Banney, Mary Azer, Andrew Dettrick

Open access · greenAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samuel Achilles FordhamDermatology, Sunshine Coast University Hospital, Birtinya, Queensland, Australia sfordham2020@gmail.com.ORCID http://orcid.org/0000-0002-4257-6919
Emily Ximin ShaoDermatology, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.ORCID http://orcid.org/0000-0003-3762-7109
Leith BanneyDermatology, Sunshine Coast University Hospital, Birtinya, Queensland, Australia.
Mary AzerOncology, Sunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.
Andrew DettrickSunshine Coast University Hospital, University of Sunshine Coast, Birtinya, Queensland, Australia.
Sunshine Coast University Hospital · AURoyal Brisbane and Women's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man in his 50s presented with an ulcerative lesion within the left axillary fold that had progressively worsened over 18 months. Biopsy revealed an ulcerative basal cell carcinoma (BCC), which was surgically managed. CT chest scans done 7 months later assessed post-treatment of radiotherapy. This revealed pulmonary lesions, which were biopsy-proven metastatic BCC. Sonidegib, a hedgehog signalling inhibitor, was used for first-line treatment. Due to progressive disease, sonidegib was ceased. Cemiplimab, a checkpoint inhibitor, was used as second-line treatment based on a phase II trial demonstrating efficacy in the setting of metastatic BCC. CT reports were initially consistent with response but after 6 months of cemiplimab treatment, repeat CT chest scans revealed a decrease in size of the previously cited pulmonary lesions.This is a rare case of BCC metastases which has limited treatment options. This case provides insight of the patient experience on such treatment.

Indexed as

Basal Cell CarcinomaLung NeoplasmsSkin NeoplasmsBiphenyl CompoundsHedgehog ProteinsHumansMalePyridinesBiphenyl CompoundsHedgehog ProteinsPyridinessonidegibDermatologyMalignant disease and immunosuppressionPlastic and reconstructive surgerySkinSkin cancer

Identifiers

PMID36599494
OpenAlexW4313482974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.