Evidence map›Paper›PMID 36599414›Full record

ArticleAnalytical chemistry2023

LipidA-IDER to Explore the Global Lipid A Repertoire of Drug-Resistant Gram-Negative Bacteria.

Xue Li Guan, Johnathan Yi-Xiong Loh, Marco Lizwan, Sharon Cui Mun Chan, Jeric Mun Chung Kwan, Tze Peng Lim, Tse Hsien Koh, Li-Yang Hsu, Bernett Teck Kwong Lee

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xue Li GuanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.ORCID 0000-0002-5189-8178
Johnathan Yi-Xiong LohLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.ORCID 0000-0001-8176-0498
Marco LizwanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.
Sharon Cui Mun ChanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.
Jeric Mun Chung KwanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.ORCID 0000-0002-1310-5464
Tze Peng LimDepartment of Pharmacy, Singapore General Hospital, Singapore 169608, Singapore.
Tse Hsien KohDepartment of Microbiology, Singapore General Hospital, Singapore 169608, Singapore.
Li-Yang HsuSaw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore.
Bernett Teck Kwong LeeLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.
Nanyang Technological University · SGSingapore General Hospital · SGAgency for Science, Technology and Research · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the global emergence of drug-resistant bacteria causing difficult-to-treat infections, there is an urgent need for a tool to facilitate studies on key virulence and antimicrobial resistant factors. Mass spectrometry (MS) has contributed substantially to the elucidation of the structure-function relationships of lipid A, the endotoxic component of lipopolysaccharide which also serves as an important protective barrier against antimicrobials. Here, we present LipidA-IDER, an automated structure annotation tool for system-level scale identification of lipid A from high-resolution tandem mass spectrometry (MS

Indexed as

Acinetobacter baumanniiAnti-Infective AgentsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialEscherichia coliGram-Negative BacteriaHumansLipid AMicrobial Sensitivity TestsPolymyxinsAnti-Bacterial AgentsAnti-Infective AgentsLipid APolymyxins

Identifiers

PMID36599414
PMCPMC9850412
OpenAlexW4313492846

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.