ArticleNature2023
Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 58 citations in OpenAlex.
- Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities.MedComm · 2026Review
- Plasticity of the infant immune system during the perinatal period.Nature reviews. Immunology · 2026Review
- Article
- ALOX15 orchestrates mitochondrial antiviral immunity and serves as a host target for anti-influenza therapy.Nature immunology · 2026Article
- Loading is not delivering: Intracellular drug retention and migration capacity govern macrophage-based drug delivery.Science advances · 2026Article
- Alveolar macrophages undergo postnatal transition from a hyperphagocytic and proinflammatory profile to a tolerogenic profile.iScience · 2026Article
- Macrophage Immune Responses in Viral Infections: Functional Plasticity and Therapeutic Targeting.Journal of microbiology and biotechnology · 2026Review
- Depletion of Neonatal Neutrophilic Cells Worsens the Outcome of E. coli Sepsis in Newborn Mice.European journal of immunology · 2026Article
- Maternal 12-HETE is associated with childhood asthma and the responses to prenatal omega-3 supplementation.Cell reports. Medicine · 2026Article
- Stage-specific neutrophil states in neonatal injury: from antimicrobial deficiency to pro-resolution repair.Frontiers in immunology · 2026Review
- Single-Cell Insights Into Macrophage Subtypes in Pulmonary Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- 12-HETE is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- DENetwork unveils non-differentially expressed genes with functional relevance across conditions through information flow perturbation.Nucleic acids research · 2025Article
- Hypoxic-ischemic brain injury in neonatal mice sequentially recruits neutrophils with dichotomous phenotype and function.Nature communications · 2025Article
- Targeting a macrophage stemness factor to mitigate diseases post respiratory viral infection.bioRxiv : the preprint server for biology · 2025Article
- Transcriptomic signatures of neonatal acute respiratory distress syndrome in a prospective cohort of respiratory distress.iScience · 2025Article
- Arachidonoyl-carnitine and arachidonoyl-coenzyme A are suitable substrates for mammalian ALOX isoforms.Journal of lipid research · 2025Article
- β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury.eLife · 2025Article
- RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A comprehensive evaluation of murine and humanERJ open research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 5 institutions in 2 countries.
Erwan PernetMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada. Erwan.pernet@mail.mcgill.ca.ORCID 0000-0003-3595-4755
Sarah SunDepartment of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.
Nicole SardenCalvin, Phoebe and Joan Snyder Institute for Chronic Diseases and Department of Critical Care, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Saideep GonaDepartment of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.
Angela NguyenCalvin, Phoebe and Joan Snyder Institute for Chronic Diseases and Department of Critical Care, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-7453-2232
Nargis KhanMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.
Martin MawhinneyDepartment of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.
Kim A TranMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.ORCID 0000-0003-0299-7417
Julia ChronopoulosMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.
Dnyandeo AmberkarMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.
Mina SadeghiDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Alexandre GrantDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Shradha WaliMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.
Renaud PrevelMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.
Jun DingMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.ORCID 0000-0001-5183-6885
James G MartinMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.
Ajitha ThanabalasuriarDepartment of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.
Bryan G YippCalvin, Phoebe and Joan Snyder Institute for Chronic Diseases and Department of Critical Care, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-5887-9551
Luis B BarreiroDepartment of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-9456-367X
Maziar DivangahiMcGill University Health Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada. Maziar.divangahi@mcgill.ca.ORCID 0000-0002-1254-6110
McGill University Health Centre · CAMcGill University · CAUniversity of Calgary · CAUniversity of Chicago · USCentre Hospitalier Universitaire Sainte-Justine · CA
Funding
MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1MNIGMS NIH HHS T32 GM007281
Abstract
Resident-tissue macrophages (RTMs) arise from embryonic precursors
Indexed as
12-Hydroxy-5,8,10,14-eicosatetraenoic AcidCell Self RenewalMacrophages, AlveolarNeutrophilsAcute Lung InjuryAnimalsAnimals, NewbornArachidonate 12-LipoxygenaseArachidonate 15-LipoxygenaseCOVID-19Disease SusceptibilityInfluenza A virusLipopolysaccharidesLungMiceOrthomyxoviridae Infections12-Hydroxy-5,8,10,14-eicosatetraenoic AcidAlox15 protein, mouseArachidonate 12-LipoxygenaseArachidonate 15-LipoxygenaseLipopolysaccharidesProstaglandins E
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.