Evidence map›Paper›PMID 36599285›Full record

ReviewThe Journal of surgical research2023

pfeRNAs-A Novel Class of Small Non-coding RNAs With Real Translational Potential.

Yuping Mei, Hamza Khan, Maria Shishikura, Shun Ishiyama, Ali Khan, Hajime Orita, Malcolm V Brock

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of surgical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  8. The Role of EMT-Related lncRNAs in Ovarian Cancer.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuping MeiDepartment of Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland. Electronic address: ymei3@jhmi.edu.
Hamza KhanDepartment of Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Maria ShishikuraDepartment of Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Shun IshiyamaDepartment of Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland; Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University, Tokyo, Japan.
Ali KhanDepartment of Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Hajime OritaDepartment of Gastroenterology and Minimally Invasive Surgery, Juntendo University, Tokyo, Japan.
Malcolm V BrockDepartment of Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland. Electronic address: mabrock@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Developing a CLIA compliant LDT for detecting plasma piR-Ls/pfeRNAs to distinguish benign and malignant lung nodulesUH3CA239137 · NCI · JOHNS HOPKINS UNIVERSITY · PI BROCK, MALCOLM V, MEI, YUPING · 2019 to 2021
$995k
Identify the target proteins of one ADC-specific and two SCC-specific pfeRNAs and investigate the mechanisms underlying the pfeRNA-protein interaction.R03CA259658 · NCI · JOHNS HOPKINS UNIVERSITY · PI MEI, YUPING · 2023 to 2024
$164k
NCI NIH HHS R03 CA259658NCI NIH HHS UH3 CA239137
6 · The paper itself

Abstract

Small non-coding RNAs (sncRNAs) are defined by being less than 200 nucleotides (nt) in length, and consequently, have been divided into many different subclasses including mature microRNA (miRNA), small interfering RNA (siRNA), piwi-interacting RNA (piRNA), protein functional effector sncRNA (pfeRNA), precursor miRNA (pre-miRNA), small nucleolar RNA (snoRNA), 5S ribosome RNA (5SrRNA), 5.8SrRNA, and small nuclear RNA (snRNA). Except for the class of pfeRNAs, the discovery, identification, biogenesis, characterization, and function of other sncRNAs have been well documented. Herein, we provide a review, written especially for clinicians, of the least understood class of functional sncRNAs, the pfeRNAs, focusing on their initial discovery, identification, unique features, function, as well as their exciting clinical translational potential.

Indexed as

MicroRNAsRNA, Small UntranslatedPiwi-Interacting RNARNA, Small InterferingMicroRNAsPiwi-Interacting RNARNA, Small InterferingRNA, Small UntranslatedpfeRNAsncRNA

Identifiers

PMID36599285
PMCPMC9911372
OpenAlexW4313399887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.