Evidence map›Paper›PMID 36599103›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Prognostic Value of Inflammatory and Nutritional Markers for Patients With Early-Stage Poorly-to Moderately-Differentiated Cervical Squamous Cell Carcinoma.

Jianfei Guo, Weiqing Lv, Zehua Wang, Yun Shang, Fan Yang, Xiaomin Zhang, Keyuan Xiao, Shangyunduo Zhang, Xiaoqi Pan, Yan Han and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jianfei GuoGraduate School of Medicine, 74652Changzhi Medical College, Changzhi, PR China.ORCID 0000-0003-1322-9990
Weiqing LvDepartment of Gynecology, 635171Yuncheng Central Hospital, The Affiliated Hospital of Shanxi Medical University, Shanxi, PR China.ORCID 0000-0002-5551-5218
Zehua WangDepartment of Anesthesiology, 117876Heji Hospital Affiliated to Changzhi Medical College, Changzhi, PR China.ORCID 0000-0002-9691-2404
Yun ShangDepartment of Gynecology, 635171Yuncheng Central Hospital, The Affiliated Hospital of Shanxi Medical University, Shanxi, PR China.ORCID 0000-0001-6423-2386
Fan YangDepartment of Central Laboratory, Changzhi People's Hospital, The Affiliated Hospital of Shanxi Medical University, Changzhi, PR China.ORCID 0000-0002-0495-4464
Xiaomin ZhangDepartment of Central Laboratory, Changzhi People's Hospital, The Affiliated Hospital of Shanxi Medical University, Changzhi, PR China.ORCID 0000-0002-2500-6471
Keyuan XiaoDepartment of Central Laboratory, Changzhi People's Hospital, The Affiliated Hospital of Shanxi Medical University, Changzhi, PR China.ORCID 0000-0002-7368-0575
Shangyunduo ZhangGraduate School of Medicine, 74652Changzhi Medical College, Changzhi, PR China.ORCID 0000-0002-6634-9120
Xiaoqi PanGraduate School of Medicine, 74652Changzhi Medical College, Changzhi, PR China.ORCID 0000-0002-3382-0932
Yan HanDepartment of Gynecology, Changzhi People's Hospital, The Affiliated Hospital of Shanxi Medical University, Changzhi, PR China.ORCID 0000-0003-2279-9127
Liang ZongDepartment of Gastrointestinal Surgery, Changzhi People's Hospital, The Affiliated Hospital of Shanxi Medical University, Changzhi, PR China.ORCID 0000-0003-4139-4571
Wenqing HuDepartment of Gastrointestinal Surgery, Changzhi People's Hospital, The Affiliated Hospital of Shanxi Medical University, Changzhi, PR China.
Shanxi Medical University · CNChangzhi Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammatory index (SII), systemic inflammation response index (SIRI), and Onodera's prognostic nutritional index (OPNI) have been reported as prognostic markers for various cancers. We evaluated the prognostic value of the NLR, PLR, MLR, SII, SIRI, and OPNI for poorly-to moderately-differentiated cervical squamous cell carcinoma (CSCC). PATIENTS AND

methodsWe retrospectively analyzed the cases of 109 patients with early-stage poorly-to moderately-differentiated CSCC who underwent radical surgery at our institution in 2014-2017. The optimal cutoff points for the NLR, PLR, MLR, SII, SIRI, and OPNI were determined by receiver operating characteristic curves. Overall survival was analyzed by the Kaplan-Meier method. We performed a multivariate analysis using the Cox proportional hazard regression model to determine the independent prognostic indicators for early-stage poorly-to moderately-differentiated CSCC.

resultsThe appropriate cutoff points were: NLR, 1.72; PLR, 111.96; MLR, .24; SII, 566.23; SIRI, 1.38; and OPNI, 52.68. The OS of the patients with a high OPNI (

conclusionThe OPNI is an independent prognostic marker for early-stage poorly-to moderately-differentiated CSCC; the NLR, PLR, MLR, SII, and SIRI are not.

Indexed as

Carcinoma, Squamous CellInflammationHumansLymphocytesPrognosisRetrospective Studiescervical squamous cell carcinomamonocyte-to-lymphocyte rationeutrophil-to-lymphocyte ratioonodera’s prognostic nutritional indexplatelet-to-lymphocyte ratio

Identifiers

PMID36599103
PMCPMC9982384
OpenAlexW4313545364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.