Evidence map›Paper›PMID 36599047›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Moving the Dial on Airway Inflammation in Response to Trikafta in Adolescents with Cystic Fibrosis.

Agathe Lepissier, Anne Sophie Bonnel, Nathalie Wizla, Laurence Weiss, Marie Mittaine, Katia Bessaci, Eitan Kerem, Véronique Houdouin, Philippe Reix, Christophe Marguet and 2 more

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Efficacy and safety of LAU-7b in a Phase 2 trial in adults with cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025
    Trial
  2. Article
  3. Effect of elexacaftor-tezacaftor-ivacaftor therapy on systemic inflammation in people with cystic fibrosis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2026
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Deleterious effect ofERJ open research · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Cystic fibrosis.Nature reviews. Disease primers · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Agathe LepissierINSERM U1151, Institut Necker Enfants Malades, Paris, France.
Anne Sophie BonnelHôpital Necker Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Nathalie WizlaHôpital Jeanne de Flandre, Lille, France.
Laurence WeissHôpital de Hautepierre, Strasbourg, France.
Marie MittaineHôpital des Enfants-CHU de Toulouse, Toulouse, France.
Katia BessaciAmerican Memorial Hospital, Reims, France.
Eitan KeremHadassah Hebrew University Medical Center, Jerusalem, Israel.
Véronique HoudouinHôpital Robert Debré, Paris, France.
Philippe ReixHôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France.
Christophe MarguetCHU de Rouen, Rouen, France.
Isabelle Sermet-GaudelusINSERM U1151, Institut Necker Enfants Malades, Paris, France.
MODUL-CF Pediatric French Network for Cystic Fibrosis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cystic FibrosisAdolescentAminophenolsBenzodioxolesCystic Fibrosis Transmembrane Conductance RegulatorDrug CombinationsHumansIndolesInflammationPyrazolesPyridinesQuinolinesRespiratory SystemAminophenolsBenzodioxolesCystic Fibrosis Transmembrane Conductance RegulatorDrug Combinationselexacaftor, ivacaftor, tezacaftor drug combinationIndolesPyrazolesPyridinesQuinolines

Identifiers

PMID36599047
PMCPMC10037474

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.