Evidence map›Paper›PMID 36598536›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

The effect of long-acting somatostatin analogues on the uptake of [

Chayenne H A M Veerman, Hinke Siebinga, Daphne M V de Vries-Huizing, Margot E T Tesselaar, Jeroen J M A Hendrikx, Marcel P M Stokkel, Else A Aalbersberg

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Transitioning from CA to NCAPhysical and engineering sciences in medicine · 2026
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  3. Article
  4. Review
  5. The cycle effect quantified: reduced tumour uptake in subsequent cycles of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  6. Letter to the editor regarding "The effect of long-acting somatostatin analogs on the uptake of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chayenne H A M VeermanDepartment of Nuclear Medicine, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Hinke SiebingaDepartment of Nuclear Medicine, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-7767-0393
Daphne M V de Vries-HuizingDepartment of Nuclear Medicine, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. d.huizing@nki.nl.ORCID http://orcid.org/0000-0003-1967-8148
Margot E T TesselaarDepartment of Medical and Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jeroen J M A HendrikxDepartment of Nuclear Medicine, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Marcel P M StokkelDepartment of Nuclear Medicine, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-8131-5690
Else A AalbersbergDepartment of Nuclear Medicine, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-4910-3794
The Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccording to IAEA/EANM/SNMMI guidelines, long-acting somatostatin analogues (LA-SSAs) should be discontinued 4-6 weeks prior to peptide receptor radionuclide therapy (PRRT) to prevent somatostatin receptor saturation. The aim of this study was to determine the effect of continued use of long-acting SSAs during PRRT on the uptake of [

methodsConsecutive patients with neuroendocrine tumours who were treated with PRRT receiving 7.4 GBq of [

resultsForty-two patients with 135 cycles of PRRT were included: 28 with lanreotide, 50 with octreotide, and 57 cycles without LA-SSAs. Uptake of [

conclusionLong-acting octreotide and lanreotide do not interfere with the uptake of [

Indexed as

Neuroendocrine TumorsOrganometallic CompoundsHumansOctreotidePositron-Emission TomographyRadionuclide ImagingReceptors, SomatostatinSomatostatincopper dotatate CU-64OctreotideOrganometallic CompoundsReceptors, SomatostatinSomatostatin[177Lu]Lu-HA-DOTATATELanreotideNETOctreotidePRRTSomatostatin analogues

Identifiers

PMID36598536
OpenAlexW4313488110

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.