Evidence map›Paper›PMID 36598250›Full record

ArticleMicrobiology spectrum2023

HSF1 Attenuates the Release of Inflammatory Cytokines Induced by Lipopolysaccharide through Transcriptional Regulation of

Hong Tan, Feifei Huang, Meiyuan Huang, Xia Wu, Zhongyi Tong

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hong TanDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Feifei HuangDepartment of Pathology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, China.
Meiyuan HuangDepartment of Pathology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, Hunan, China.
Xia WuDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhongyi TongDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0003-3458-8976
Central South University · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy plays an important role in endotoxemic mice, and heat shock factor 1 (HSF1) plays a crucial protective role in endotoxemic mice. However, the protective mechanisms of HSF1 are poorly understood. In this text, bioinformatics analysis, chromatin immunoprecipitation, and electrophoresis mobility shift assay were employed to investigate the underlying mechanisms. The results showed that the release of inflammatory cytokines increased and autophagy decreased significantly in

Indexed as

CytokinesLipopolysaccharidesAnimalsGene Expression RegulationHeat Shock Transcription FactorsMiceRNA, Small InterferingCytokinesHeat Shock Transcription FactorsHsf1 protein, mouseLipopolysaccharidesRNA, Small Interferingautophagy related gene 10 (Atg10)endotoxemiaheat shock factor 1 (HSF1)inflammatory cytokineslipopolysaccharide (LPS)

Identifiers

PMID36598250
PMCPMC9927406
OpenAlexW4313488612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.