Evidence map›Paper›PMID 36598044›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Phenethyl isothiocyanate protects against cyclophosphamide-induced nephrotoxicity via nuclear factor E2-related factor 2 pathway in rats.

Ayşe Burçin Uyumlu, Basri Satılmış, Buğrahan Atıcı, Aslı Taşlıdere

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ayşe Burçin UyumluDepartment of Biochemistry, İnönü University, 44280 Malatya, Turkey.ORCID 0000-0001-9517-9274
Basri SatılmışHepatology Research Laboratory, Liver Transplantation Institute, İnönü University, 44280 Malatya, Turkey.
Buğrahan AtıcıDepartment of Biochemistry, İnönü University, 44280 Malatya, Turkey.
Aslı TaşlıdereDepartment of Histology and Embryology, İnönü University, 44280 Malatya, Turkey.
Inonu University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenethyl isothiocyanate (PEITC), a secondary metabolite in Cruciferous plants, exerts chemopreventive and antioxidant effects. However, its therapeutic potential in cyclophosphamide (CP)-induced nephrotoxicity is not clear. So, we focused to research on the effect of PEITC against renal toxicity caused by CP and its relationship to the Nrf2 signaling mechanism. Thirty female Wistar albino rats were allocated to three groups: control (

Indexed as

NF-E2-Related Factor 2NF-kappa BAnimalsAntioxidantsCyclophosphamideIsothiocyanatesKidneyOxidative StressRatsRats, WistarSirtuin 1AntioxidantsCyclophosphamideIsothiocyanatesNF-E2-Related Factor 2NF-kappa Bphenethyl isothiocyanateSirtuin 1CyclophosphamidenephrotoxicityNrf2phenethyl isothiocyanatesirtuin1

Identifiers

PMID36598044
PMCPMC10041055
OpenAlexW4313488189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.