ArticleNeurospine2022
Prevalence, Distribution, and Concomitance of Whole-Spine Ossification of the Posterior Longitudinal Ligament and Ossification of the Ligament Flavum in South Koreans: A Whole-Spine-CT-Based Cross-Sectional Study.
Article in Neurospine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Risk factors for symptomatic hematoma following cervical spine surgery: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Diagnostic performance of zero-echo time (ZTE) MRI for preoperative evaluation of cervical OPLL complicated with dural ossification (DO): a retrospective study.Skeletal radiology · 2026Article
- Risk of Ossification of the Posterior Longitudinal Ligament (OPLL) following gout diagnosis: a nationwide cohort study.International orthopaedics · 2026Article
- Prevalence and Radiological Features of Thoracic Ossification of the Ligamentum Flavum in Korea-A Retrospective Comparative Cohort Study Using MRI.Journal of clinical medicine · 2026Article
- Ossification of the Posterior Longitudinal Ligament in a Chilean Population: A CT-Based Prevalence Study in Patients Aged 60 Years and Older.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Thoracic controllable antedisplacement and fusion in the treatment of multilevel thoracic ossification of the posterior longitudinal ligament: a case series with technical notes.Journal of orthopaedic surgery and research · 2025Article
- Biological mechanisms underlying the ossification of ligamentum flavum and potential therapeutic targets derived from current research.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Review
- Article
- Correlation Between the Severity of Multifidus Fatty Degeneration and the Size of Ossification of Posterior Longitudinal Ligament at Each Spinal Level.Neurospine · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNo studies assessing the prevalence of ossification of the spinal ligament were conducted using whole-spine positron emission tomography and computed tomography (PET-CT) in healthy Koreans. We aimed to determine the prevalence of ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligament flavum (OLF) in healthy Koreans using whole-body PET-CT.
methodsWe reviewed whole-body PET-CT images captured during general health checkups at the General Health Promotion Center of our institution from January 2015 to 2020. OPLL and OLF were identified by the presence of heterotopic ossification in the posterior longitudinal ligament and ligament flavum on axial and sagittal PET-CT images.
resultsA total of 1,934 adults (1,645 men, 289 women) were included. The mean age was 48.05 years (range, 28-86 years). Among the 1,934 patients, 173 had OPLL (8.9%). The most commonly involved cervical vertebra levels arranged according to frequency were C4, C5, C3, and C6. OLF was observed in 125 patients (6.5%). The most commonly involved thoracic levels were T10, T11, and T5. The prevalence of OPLL and OLF was the highest in patients aged 60-69 years. Among the C-OPLL patients, 15.1% had T-OPLL, 5.0% had L-OPLL, and 25.8% had T-OLF.
conclusionOur study revealed the prevalence of OPLL and OLF in healthy Korean subjects. It was consistent with that in other Asian countries. The presence of OPLL and OLF at most locations correlated with the presence or absence of spinal ossification at other locations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.