Evidence map›Paper›PMID 36597603›Full record

ReviewCurrent cardiology reviews2023

Drug-Eluting Stent Restenosis: Modern Approach to a Classic Challenge.

Teodora Donisan, Luai Madanat, Dinu V Balanescu, Amy Mertens, Simon Dixon

Registry-linked trialAbstract readReview
In one paragraph

Review in Current cardiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06055673 (Angiotensin Converting Enzyme rs), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06055673 unknown statusnot on this map

Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases in Sohag Hospital University.

TypeobservationalSponsorSohag UniversityRan2023 to 2023Enrolled182ConditionsAngiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery DiseasesArmsDNA extraction AND Real- time polymerase chain reaction analysis to POLYMORPHISM OF in in-stent restenosis (ISR) in CAD
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Teodora DonisanDepartment of Internal Medicine, Beaumont Hospital, Royal Oak, MI, 48073, USA.
Luai MadanatDepartment of Internal Medicine, Beaumont Hospital, Royal Oak, MI, 48073, USA.
Dinu V BalanescuDepartment of Internal Medicine, Beaumont Hospital, Royal Oak, MI, 48073, USA.
Amy MertensDepartment of Cardiovascular Medicine, Beaumont Hospital, Royal Oak, MI, 48073, USA.
Simon DixonDepartment of Cardiovascular Medicine, Beaumont Hospital, Royal Oak, MI, 48073, USA.
Beaumont Hospital, Royal Oak · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In-stent restenosis (ISR) is a recognized complication following percutaneous coronary intervention in which the luminal diameter is narrowed through neointimal hyperplasia and vessel remodeling. Although rates of ISR have decreased in most recent years owing to newer generation drug-eluting stents, thinner struts, and better intravascular imaging modalities, ISR remains a prevalent dilemma that proves to be challenging to manage. Several factors have been proposed to contribute to ISR formation, including mechanical stent characteristics, technical factors during the coronary intervention, and biological aspects of drug-eluting stents. Presentation of ISR can range from asymptomatic to late myocardial infarction and could be difficult to differentiate from acute thrombus formation. No definite guidelines are present on the management of ISR. In this review, we will discuss the mechanisms underlying ISR and provide insight into patient-related and procedural risk factors contributing to ISR, in addition to highlighting common treatment approaches utilized in the management of ISR.

Indexed as

Coronary RestenosisDrug-Eluting StentsHeart Valve DiseasesPercutaneous Coronary InterventionCoronary AngiographyHumansProsthesis DesignRisk FactorsStentsTreatment Outcomebare metal stentbrachytherapyDES-ISRdrug-eluting stentIn-stent restenosispercutaneous coronary intervention

Identifiers

PMID36597603
PMCPMC10280993
OpenAlexW4313488687

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.