ArticleJournal of animal science and biotechnology2023
A meta-analysis on the effects of probiotics on the performance of pre-weaning dairy calves.
Article in Journal of animal science and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The trial behind it
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Who cites it
24 citing papers in PubMed.
- Placebo-resistant gut bacteria:Frontiers in cellular and infection microbiology · 2024Trial
- Effects of commercial direct-fed microbials and zinc-methionine supplements on growth performance in preweaning Holstein calves under commercial rearing conditions.Veterinary and animal science · 2026Article
- Modulation of Early-Life Calf Gut Microbiota by Bacteriocin-Producing Lactiplantibacillus pentosus AA86 and Pediococcus pentosaceus AA94.MicrobiologyOpen · 2026Article
- Probiotics in Poultry: A Comprehensive Review of Mechanisms, Applications, and Future Directions.Veterinary sciences · 2026Review
- Impact of lactic acid bacteria andVeterinary and animal science · 2026Article
- The potential of yeast culture for alleviating enterotoxigenicAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- Multi-Omics Analysis Reveals That Alkaline Mineral Complex Reshapes Rumen Mucosal Microbiota and Metabolites and Enhances Rumen Epithelial Barrier Function in Fattening Cattle.Animals : an open access journal from MDPI · 2026Article
- Harnessing the early-life gut microbiome for sustainable ruminant production.Animal microbiome · 2026Review
- Effects of inactivatedAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- A machine learning-derived genomic dataset from bacteria frequently reported as probiotics.Frontiers in bioinformatics · 2026Article
- Gut microbiota in diarrheic and healthy calves: comparative analysis of 16S rRNA gene full-length sequences.BMC veterinary research · 2025Article
- The Role of Probiotics in Enhancing Animal Health: Mechanisms, Benefits, and Applications in Livestock and Companion Animals.Animals : an open access journal from MDPI · 2025Review
- Effects ofAnimals : an open access journal from MDPI · 2025Article
- Effect of Multi-Species Probiotic Supplementation on Fecal Microbiota in Pre-Weaned Holstein Dairy Calves in California.Microorganisms · 2025Article
- Analysis of the Microbiota of Milk from Holstein-Friesian Dairy Cows Fed a Microbial Supplement.Animals : an open access journal from MDPI · 2025Article
- A Narrative Review on the Impact of Probiotic Supplementation on Muscle Development, Metabolic Regulation, and Fiber Traits Related to Meat Quality in Broiler Chickens.Microorganisms · 2025Review
- Correlation between gastrointestinal morphological changes, enteric microbiota, and changes in live weight in dairy calves.JDS communications · 2025Article
- Effects ofAnimals : an open access journal from MDPI · 2025Article
- Use of biotics in animals: impact on nutrition, health, and food production.Journal of animal science · 2025Review
- Immuno-physiological role of exogenous enzymes supplementation in heat stressed growing calves.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundProbiotics have been used in livestock production for many years, but information on their benefits during the early life of calves is inconsistent. This study aimed to assess the effects of probiotics on the performance of pre-weaning dairy calves and identify the factors influencing their effect sizes.
resultsForty-nine studies were selected for meta-analysis based on the inclusion and exclusion criteria. The study qualities were evaluated using a predefined risk assessment tool following GRADE guidelines. Meta-analysis results showed that probiotics increased the growth performance (body weight by 1.988 kg and average daily gain by 40.689 g/d), decreased digestibility and feed efficiency (feed conversion rate by 0.073), altered rumen parameter (decreased acetate by 2.815 mmol/L and increased butyrate by 0.788 mmol/L), altered blood parameter (decreased AST by 4.188 U/L, increased BHBA by 0.029 mmol/L and IgG by 0.698 g/L), increased faecal parameter (faecal bacteria counts by 0.680 log
conclusionsProbiotics could improve the growth performance, feed intake and efficiency, rumen fermentation, immune and antioxidant capacity, and health of pre-weaning calves. However, the effect sizes were related to the dosage, composition, and supplementation methods of probiotics.
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