Evidence map›Paper›PMID 36597120›Full record

Observational studyBMC women's health2023

Association between history of childbirth and chronic, functionally significant back pain in later life.

Michelle Zhang, Corinne Cooley, Maisa S Ziadni, Ian Mackey, Pamela Flood

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04091321 (Association Between Chronic Headache and Back Pain With Childbirth), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04091321 completednot on this map

Association Between Chronic Headache and Back Pain With Childbirth

TypeobservationalSponsorStanford UniversityRan2019 to 2020Enrolled1,112ConditionsHeadache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Michelle ZhangSchool of Medicine, Stanford University, Palo Alto, CA, USA.
Corinne CooleyStanford Health Care, Palo Alto, California, USA.
Maisa S ZiadniDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, 300 Pasteur Dr, Palo Alto, CA, 94305, USA.
Ian MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, 300 Pasteur Dr, Palo Alto, CA, 94305, USA.
Pamela FloodDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, 300 Pasteur Dr, Palo Alto, CA, 94305, USA. pflood@stanford.edu.ORCID 0000-0001-7023-3924
Stanford University · USSeattle Pacific University · USStanford Health Care · USStanford Medicine · US

Funding

Single Session Pain Catastrophizing Class: Efficacy & Mechanisms for Reducing Opioid Use Among Chronic Pain PatientsK23DA047473 · NIDA · STANFORD UNIVERSITY · PI ZIADNI, MAISA · 2019 to 2023
$796k
NIDA NIH HHS K23 DA047473
6 · The paper itself

Abstract

backgroundBack pain is more prevalent among women than men. The association with sex could be related to pregnancy and childbirth, unique female conditions. This association has not been thoroughly evaluated.

methodsUsing a retrospective cohort design, we evaluated the relationship between history of childbirth on the prevalence and severity of functionally consequential back pain in 1069 women from a tertiary care pain management clinic. Interactions among preexisting, acute peripartum, and subsequent back pain were evaluated as secondary outcomes among the parous women using logistic and linear regression as appropriate.

resultsThe women who had given birth had a higher risk for functionally significant back pain compared to women who had not given birth (85% vs 77%, p < 0.001, Risk Ratio 1.11 [1.04-1.17]). The association was preserved after correction for age, weight, and race. Back pain was also more slightly severe (Numerical Rating Score for Pain 7[5-8] vs 6[5-7] out of 10, p = 0.002). Women who recalled severe, acute postpartum back pain had a higher prevalence of current debilitating back pain (89% vs 75%, Risk Ratio 1.19 (1.08-1.31), p = 0.001). Twenty-eight percent of acute postpartum back pain never resolved and 40% reported incomplete resolution.

conclusionsA history of pregnancy and childbirth is a risk factor for chronic functionally significant back pain in women. Severe acute postpartum back pain is a risk factor for future disability suggesting that the peripartum period may provide an important opportunity for intervention. Early recognition and management may mitigate future disability.

trial registrationThe study was registered with clinicaltrials.gov as "Association Between Chronic Headache and Back Pain with Childbirth" (NCT04091321) on 16/09/2019 before it was initiated.

Indexed as

Back PainParturitionDelivery, ObstetricFemaleHumansPostpartum PeriodPregnancyRetrospective StudiesAcute painBack painChildbirthChronic painPregnancy

Identifiers

PMID36597120
PMCPMC9809019
OpenAlexW4313524075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.