Evidence map›Paper›PMID 36597102›Full record

ArticleBMC public health2023

A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations.

Maria Carolina Elias, Svetoslav Nanev Slavov, Alex Ranieri Jeronimo Lima, Antonio Jorge Martins, Claudia Renata Dos Santos Barros, Debora Botequio Moretti, Eduardo L Araujo, Elaine Cristina Marqueze, Gabriela Ribeiro, Gabriela Mauric Frossard Ribeiro and 14 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 1 country.

Maria Carolina EliasInstituto Butantan, São Paulo, Brazil. carolina.eliassabbaga@butantan.gov.br.ORCID 0000-0002-0501-8280
Svetoslav Nanev SlavovUniversity of São Paulo, Ribeirão Preto Medical School, Blood Center of Ribeirão Preto, Ribeirão Preto, Brazil.
Alex Ranieri Jeronimo LimaInstituto Butantan, São Paulo, Brazil.
Antonio Jorge MartinsInstituto Butantan, São Paulo, Brazil.
Claudia Renata Dos Santos BarrosInstituto Butantan, São Paulo, Brazil.
Debora Botequio MorettiInstituto Butantan, São Paulo, Brazil.
Eduardo L AraujoLoccus, São Paulo, Brazil.
Elaine Cristina MarquezeInstituto Butantan, São Paulo, Brazil.
Gabriela RibeiroInstituto Butantan, São Paulo, Brazil.
Gabriela Mauric Frossard RibeiroInstituto Butantan, São Paulo, Brazil.
Jardelina Souza Todao BernardinoInstituto Butantan, São Paulo, Brazil.
Jaqueline Reginato KoserInstituto Butantan, São Paulo, Brazil.
Luan Gaspar ClementeCentro de Genomica Funcional, ESALQ-USP, Piracicaba, São Paulo, Brasil.
Luiz Aurelio Campos CrispinInstituto Butantan, São Paulo, Brazil.
Luiz Carlos Junior AlcantaraInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Minas Gerais, Brazil.
Luiz Lehmann CoutinhoCentro de Genomica Funcional, ESALQ-USP, Piracicaba, São Paulo, Brasil.
Marta GiovanettiInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Minas Gerais, Brazil.
Quetura Oliveira SilvaInstituto Butantan, São Paulo, Brazil.
Raul Machado NetoInstituto Butantan, São Paulo, Brazil.
Ricardo HaddadInstituto Butantan, São Paulo, Brazil.
Simone KashimaUniversity of São Paulo, Ribeirão Preto Medical School, Blood Center of Ribeirão Preto, Ribeirão Preto, Brazil.
Vincent Louis VialaInstituto Butantan, São Paulo, Brazil.
Dimas Tadeu CovasInstituto Butantan, São Paulo, Brazil.
Sandra Coccuzzo SampaioInstituto Butantan, São Paulo, Brazil. sandra.coccuzzo@butantan.gov.br.
Instituto Butantan · BRUniversidade de São Paulo · BRFundação Oswaldo Cruz · BRGenomic (Brazil) · BR

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
Conselho Nacional de Desenvolvimento Científico e Tecnológico 301677/2018-2Conselho Nacional de Desenvolvimento Científico e Tecnológico 304353/2019-1Conselho Nacional de Desenvolvimento Científico e Tecnológico 306199/2018-1Conselho Nacional de Desenvolvimento Científico e Tecnológico 312003/2020-0Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/202.248/2018 (238504)Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/202.665/2019(247400)Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07467-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/15826-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/00694-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/10127-1ICEGEB Contract CRP/20/03.ICEGEB CRP/BRA20-03NIAID NIH HHS U01 AI151698NIH HHS U01 AI151698
6 · The paper itself

Abstract

backgroundBrazil has been dramatically hit by the SARS-CoV-2 pandemic and is a world leader in COVID-19 morbidity and mortality. Additionally, the largest country of Latin America has been a continuous source of SARS-CoV-2 variants and shows extraordinary variability of the pandemic strains probably related to the country´s outstanding position as a Latin American economical and transportation hub. Not all regions of the country show sufficient infrastructure for SARS-CoV-2 diagnosis and genotyping which can negatively impact the pandemic response.

methodsDue to this reason and to disburden the diagnostic system of the inner São Paulo State, the Butantan Institute established the Mobile Laboratory (in Portuguese: LabMovel) for SARS-CoV-2 testing which started a trip of the most important "hotspots" of the most populous Brazilian region. The LabMovel initiated in two important cities of the State: Aparecida do Norte (an important religious center) and the Baixada Santista region which incorporates the port of Santos, the busiest in Latin America. The LabMovel was fully equipped with an automatized system for SARS-CoV-2 diagnosis and sequencing/genotyping. It also integrated the laboratory systems for patient records and results divulgation including in the Federal Brazilian Healthcare System.

resultsCurrently,16,678 samples were tested, among them 1,217 from Aparecida and 4,564 from Baixada Santista. We tracked the delta introductio in the tested regions with its high diversification. The established mobile SARS-CoV-2 laboratory had a major impact on the Public Health System of the included cities including timely delivery of the results to the healthcare agents and the Federal Healthcare system, evaluation of the vaccination status of the positive individuals in the background of exponential vaccination process in Brazil and scientific and technological divulgation of the fieldwork to the most vulnerable populations.

conclusionsThe SARS-CoV-2 pandemic has demonstrated worldwide the importance of science to fight against this viral agent and the LabMovel shows that it is possible to integrate researchers, clinicians, healthcare workers and patients to take rapid actions that can in fact mitigate this and other epidemiological situations.

Indexed as

COVID-19SARS-CoV-2BrazilCOVID-19 TestingHumansPandemicsVulnerable PopulationsBrazilCOVID-19LabMovelMolecular surveillanceReal-time detectionSARS-CoV-2

Identifiers

PMID36597102
PMCPMC9810251
OpenAlexW4313524085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.