Trial reportTobacco control2024
Randomised experiment for the effect of 'Tobacco-Free Nicotine' messaging on current e-cigarette users' perceptions, preferences and intentions.
Trial report in Tobacco control, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Evaluation of vaping cessation infographics among e-cigarette users: A cross-sectional, mixed-methods study.Tobacco prevention & cessation · 2026Article
- Prospective associations between nicotine type and the continuation of youth e-cigarette use.BMC public health · 2025Article
- Responses to e-cigarette nicotine source descriptors: results from a randomised experiment.Tobacco control · 2025Article
- Tobacco control messages for individuals who use both cigarettes and e-cigarettes: a randomised trial comparing biomarker outcome with cessation experience narratives.Tobacco control · 2025Article
- Decoding Vaping: Empowering Youth Through Media Literacy Based E-cigarette Educational Program.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Developing a media literacy-based e-cigarette education program via medical record systems.Tobacco prevention & cessation · 2025Article
- The trade of illicit cigarettes in Ghana: Insights from a policy synthesis and qualitative study.Tobacco prevention & cessation · 2025Article
- Synthetic nicotine descriptors: awareness and impact on perceptions of e-cigarettes among US youth.Tobacco control · 2024Article
- e-Cigarette Tobacco Flavors, Public Health, and Toxicity: Narrative Review.Online journal of public health informatics · 2024Review
- Vaping: Public Health, Social Media, and Toxicity.Online journal of public health informatics · 2024Article
- Nicotine information disclosed online by e-cigarette brands popular with young people.Tobacco prevention & cessation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIt is unclear whether emerging synthetic tobacco-free nicotine superiority messages such as 'better flavor and better experience' and 'no residual impurities of tobacco-derived nicotine' may impact consumer perception and product choice between synthetic and tobacco-derived nicotine vaping products.
methodsThrough a 2022 online survey of current e-cigarette users, we identified synthetic nicotine never users for randomisation into an embedded between-subjects experiment. The test group (n=186) viewed a tobacco-free nicotine message versus no message control (n=168). Multivariable regressions assessed messaging effects on three comparative measures between tobacco-free and tobacco-derived nicotine: harm perception, purchase intention and willingness to pay.
resultsParticipants (n=354; age, mean (SD)=34.6 (11.1) years old) were recruited from geographically diverse regions with 27.7% rural residents. The overall sample comprised 44.1% females, 73.5% non-Hispanic white and 71.8% daily e-cigarette users. Sociodemographics and tobacco use status were not significantly different between two randomised groups. The test group (vs control) reported a higher intention to use tobacco-free than tobacco-derived nicotine vaping products (adjusted OR (AOR)=2.4, 95% CI 1.3 to 4.4, p=0.006) and willingness to pay more for tobacco-free nicotine vaping products (AOR=2.6, 95% CI 1.2 to 5.8, p=0.02). Urban (vs rural) synthetic-naïve vapers had lower harm perception (AOR=2.0, 95% CI 1.1 to 3.6, p=0.02) and higher intention to use tobacco-free than tobacco-derived nicotine vaping products (AOR=2.2, 95% CI 1.1 to 4.5, p=0.04); infrequent vapers were more willing to pay more for tobacco-free nicotine vaping products (AOR=1.1, 95% CI 1.03 to 1.17, p=0.002).
conclusionTobacco-free nicotine marketing message may prompt the transition to and promote a price premium for such products. With the proliferation of products in the market, comprehensive regulation of emerging synthetic vaping products is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.