Evidence map›Paper›PMID 36596655›Full record

SynthesisRMD open2023

Non-pharmacological interventions to promote work participation in people with rheumatic and musculoskeletal diseases: a systematic review and meta-analysis from the EULAR taskforce on healthy and sustainable work participation.

Maarten H P Butink, Casper Webers, Suzanne M M Verstappen, Louise Falzon, Neil Betteridge, Dieter Wiek, Anthony D Woolf, Tanja A Stamm, Gerd R Burmester, Johannes W J Bijlsma and 2 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 6 countries.

Maarten H P ButinkDepartment of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.ORCID 0000-0002-5999-9782
Casper WebersDepartment of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.ORCID 0000-0003-3011-8547
Suzanne M M VerstappenCentre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Louise FalzonHealth Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK.
Neil BetteridgeDirectory, Neil Betteridge Associates, London, UK.
Dieter WiekPatient Research Partner, EULAR/PARE, Zürich, Switzerland.
Anthony D WoolfBone and Joint Research Group, Royal Cornwall Hospital, Truro, UK.
Tanja A StammSection for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3073-7284
Gerd R BurmesterRheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany.ORCID 0000-0001-7518-1131
Johannes W J BijlsmaDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-0128-8451
Robin ChristensenSection for Biostatistics and Evidence-Based Research, Frederiksberg Hospital Parker Institute, Copenhagen, Denmark.
Annelies BoonenDepartment of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands a.boonen@mumc.nl.ORCID 0000-0003-0682-9533
Maastricht University Medical Centre · NLCharité - Universitätsmedizin Berlin · DEEuropean League Against Rheumatism · CHManchester Academic Health Science Centre · GBMore Associates · GBRoyal Cornwall Hospital · GBStatistics Austria · ATUniversity Medical Center Utrecht · NLUniversity of Sheffield · GBUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo summarise the evidence on effectiveness of non-pharmacological (ie, non-drug, non-surgical) interventions on work participation (sick leave, work status and presenteeism) in people with rheumatic and musculoskeletal diseases (RMDs).

methodsA systematic review of randomised controlled trials (RCTs) and longitudinal observational studies (LOS) was performed. Qualitative (RCTs/LOS) and quantitative (RCTs) evidence syntheses were conducted. Mixed-effects restricted maximum likelihood models were used to combine effect estimates, using standardised mean differences (SMDs) as the summary measure for each outcome domain separately, with a negative SMD favouring the intervention over comparator. Subgroup analyses were performed for type of RMD, risk status at baseline regarding adverse work outcomes and intervention characteristics.

resultsOf 10 153 records, 64 studies (37 RCTs and 27 LOS; corresponding to

conclusionIn people with RMDs, empirical evidence shows that non-pharmacological interventions have small effects on work participation. Effectiveness depends on contextual factors such as disease, population risk status, intervention characteristics and outcome of interest, highlighting the importance of tailoring interventions.

Indexed as

Musculoskeletal DiseasesHealth StatusHumansOccupational therapyPsychologyRehabilitation

Identifiers

PMID36596655
PMCPMC10098260
OpenAlexW4313462067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.